Selective over-expression of mRNA coding for 90 KDa stress-protein in human ovarian cancer

A. M. Mileo; M. Fanuele; F. Battaglia; G. Scambia; P. Benedetti-Panici; S. Mancuso; U. Ferrini

Selective over-expression of mRNA coding for 90 KDa stress-protein in human ovarian cancer

A. M. Mileo, M. Fanuele, F. Battaglia, G. Scambia, P. Benedetti-Panici, S. Mancuso, U. Ferrini

Istituto Regina Elena

Research output: Contribution to journal › Article › peer-review

Abstract

The mRNA expression of the KDa stress-protein (SP) was assayed in normal and neoplastic human ovary. It was found that the expression level is low in normal ovary and in benign tumors and increases in the more advanced stages of ovarian cancer. A low level of mRNA coding for the 70 KDa SP - the most prominent among the inducible SPs - was constantly found in all specimens. No relationship was observed between SP 90 mRNA abundance and the receptor status of epidermal growth factor, estrogen and progesterone.

Original language	English
Pages (from-to)	903-906
Number of pages	4
Journal	Anticancer Research
Volume	10
Issue number	4
Publication status	Published - 1990

Keywords

mRNA over-expression
ovarian cancer
stress protein

ASJC Scopus subject areas

Cancer Research
Oncology

Cite this

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title = "Selective over-expression of mRNA coding for 90 KDa stress-protein in human ovarian cancer",

abstract = "The mRNA expression of the KDa stress-protein (SP) was assayed in normal and neoplastic human ovary. It was found that the expression level is low in normal ovary and in benign tumors and increases in the more advanced stages of ovarian cancer. A low level of mRNA coding for the 70 KDa SP - the most prominent among the inducible SPs - was constantly found in all specimens. No relationship was observed between SP 90 mRNA abundance and the receptor status of epidermal growth factor, estrogen and progesterone.",

keywords = "mRNA over-expression, ovarian cancer, stress protein",

author = "Mileo, {A. M.} and M. Fanuele and F. Battaglia and G. Scambia and P. Benedetti-Panici and S. Mancuso and U. Ferrini",

year = "1990",

language = "English",

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journal = "Anticancer Research",

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T1 - Selective over-expression of mRNA coding for 90 KDa stress-protein in human ovarian cancer

AU - Mileo, A. M.

AU - Fanuele, M.

AU - Battaglia, F.

AU - Scambia, G.

AU - Benedetti-Panici, P.

AU - Mancuso, S.

AU - Ferrini, U.

PY - 1990

Y1 - 1990

N2 - The mRNA expression of the KDa stress-protein (SP) was assayed in normal and neoplastic human ovary. It was found that the expression level is low in normal ovary and in benign tumors and increases in the more advanced stages of ovarian cancer. A low level of mRNA coding for the 70 KDa SP - the most prominent among the inducible SPs - was constantly found in all specimens. No relationship was observed between SP 90 mRNA abundance and the receptor status of epidermal growth factor, estrogen and progesterone.

AB - The mRNA expression of the KDa stress-protein (SP) was assayed in normal and neoplastic human ovary. It was found that the expression level is low in normal ovary and in benign tumors and increases in the more advanced stages of ovarian cancer. A low level of mRNA coding for the 70 KDa SP - the most prominent among the inducible SPs - was constantly found in all specimens. No relationship was observed between SP 90 mRNA abundance and the receptor status of epidermal growth factor, estrogen and progesterone.

KW - mRNA over-expression

KW - ovarian cancer

KW - stress protein

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M3 - Article

C2 - 2382987

AN - SCOPUS:0025287603

VL - 10

SP - 903

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JO - Anticancer Research

JF - Anticancer Research

SN - 0250-7005

IS - 4

ER -

Selective over-expression of mRNA coding for 90 KDa stress-protein in human ovarian cancer

Abstract

Keywords

ASJC Scopus subject areas

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