Selective storage of p-hydroxy-d-amphetamine in the dopaminergic nerve terminals

A. Jori, S. Caccia, A. Guiso, M. Ballabio, S. Garattini

Research output: Contribution to journalArticle

Abstract

Repeated treatments with p-hydroxy-d-amphetamine (pOHdA) result in it accumulating on the striatum but not in the brainstem. Agents which destroy dopaminergic nerve terminals (6-hydroxydopa mine), or release dopamine (reserpine, tetrabenazine, pimozide) from nerve endings, reduce the accumulation of pHOdA in the striatum. but do not affect its levels in the brainstem or plasma.

Original languageEnglish
Pages (from-to)1205-1207
Number of pages3
JournalBiochemical Pharmacology
Volume28
Issue number7
DOIs
Publication statusPublished - Apr 1 1979

ASJC Scopus subject areas

  • Pharmacology

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