Self-assessed health status changes in a community cohort of people with multiple sclerosis

11years of follow-up

A. Giordano, G. Ferrari, D. Radice, G. Randi, L. Bisanti, A. Solari

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Background and purpose: Few data are available on the health status of people with multiple sclerosis (PwMS) in the community. We assessed changes in self-perceived health status and health related quality of life of a community-based cohort of PwMS over a decade, and identified predictors of such changes. Methods: In 1999 we started the POSMOS study (Postal Survey of Self-Assessed Health of MS Adults and their Significant Others) on a random sample of 251 adults with MS from the Milan area (mean age 42years, range 18-71years), and prospectively assessed changes in self-perceived health status over 11years. Participants completed the Multiple Sclerosis Quality-of-Life-54 (MSQOL-54) and a general/clinical questionnaire. We re-assessed the cohort in 2004 and 2010, sending the same questionnaires plus the Chicago Multiscale Depression Inventory. Results: There were 205 (86%) respondents in 2004, 171 (74%) in 2010; 28 (11%) died during the study. Severely impaired [self-determined Expanded Disability Status Scale (EDSS)>6.5] increased from 19% to 32%. One-fifth remained fully ambulatory (EDSS

Original languageEnglish
Pages (from-to)681-688
Number of pages8
JournalEuropean Journal of Neurology
Volume20
Issue number4
DOIs
Publication statusPublished - Apr 2013

Fingerprint

Health Status
Multiple Sclerosis
Quality of Life
Equipment and Supplies
Surveys and Questionnaires
Health

Keywords

  • Depression
  • Longitudinal study
  • Multiple sclerosis
  • Patient-reported outcomes
  • Quality of life

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Self-assessed health status changes in a community cohort of people with multiple sclerosis : 11years of follow-up. / Giordano, A.; Ferrari, G.; Radice, D.; Randi, G.; Bisanti, L.; Solari, A.

In: European Journal of Neurology, Vol. 20, No. 4, 04.2013, p. 681-688.

Research output: Contribution to journalArticle

@article{ba72872d4eda426aade56791a6c7a892,
title = "Self-assessed health status changes in a community cohort of people with multiple sclerosis: 11years of follow-up",
abstract = "Background and purpose: Few data are available on the health status of people with multiple sclerosis (PwMS) in the community. We assessed changes in self-perceived health status and health related quality of life of a community-based cohort of PwMS over a decade, and identified predictors of such changes. Methods: In 1999 we started the POSMOS study (Postal Survey of Self-Assessed Health of MS Adults and their Significant Others) on a random sample of 251 adults with MS from the Milan area (mean age 42years, range 18-71years), and prospectively assessed changes in self-perceived health status over 11years. Participants completed the Multiple Sclerosis Quality-of-Life-54 (MSQOL-54) and a general/clinical questionnaire. We re-assessed the cohort in 2004 and 2010, sending the same questionnaires plus the Chicago Multiscale Depression Inventory. Results: There were 205 (86{\%}) respondents in 2004, 171 (74{\%}) in 2010; 28 (11{\%}) died during the study. Severely impaired [self-determined Expanded Disability Status Scale (EDSS)>6.5] increased from 19{\%} to 32{\%}. One-fifth remained fully ambulatory (EDSS",
keywords = "Depression, Longitudinal study, Multiple sclerosis, Patient-reported outcomes, Quality of life",
author = "A. Giordano and G. Ferrari and D. Radice and G. Randi and L. Bisanti and A. Solari",
year = "2013",
month = "4",
doi = "10.1111/ene.12028",
language = "English",
volume = "20",
pages = "681--688",
journal = "European Journal of Neurology",
issn = "1351-5101",
publisher = "Wiley-Blackwell Publishing Ltd",
number = "4",

}

TY - JOUR

T1 - Self-assessed health status changes in a community cohort of people with multiple sclerosis

T2 - 11years of follow-up

AU - Giordano, A.

AU - Ferrari, G.

AU - Radice, D.

AU - Randi, G.

AU - Bisanti, L.

AU - Solari, A.

PY - 2013/4

Y1 - 2013/4

N2 - Background and purpose: Few data are available on the health status of people with multiple sclerosis (PwMS) in the community. We assessed changes in self-perceived health status and health related quality of life of a community-based cohort of PwMS over a decade, and identified predictors of such changes. Methods: In 1999 we started the POSMOS study (Postal Survey of Self-Assessed Health of MS Adults and their Significant Others) on a random sample of 251 adults with MS from the Milan area (mean age 42years, range 18-71years), and prospectively assessed changes in self-perceived health status over 11years. Participants completed the Multiple Sclerosis Quality-of-Life-54 (MSQOL-54) and a general/clinical questionnaire. We re-assessed the cohort in 2004 and 2010, sending the same questionnaires plus the Chicago Multiscale Depression Inventory. Results: There were 205 (86%) respondents in 2004, 171 (74%) in 2010; 28 (11%) died during the study. Severely impaired [self-determined Expanded Disability Status Scale (EDSS)>6.5] increased from 19% to 32%. One-fifth remained fully ambulatory (EDSS

AB - Background and purpose: Few data are available on the health status of people with multiple sclerosis (PwMS) in the community. We assessed changes in self-perceived health status and health related quality of life of a community-based cohort of PwMS over a decade, and identified predictors of such changes. Methods: In 1999 we started the POSMOS study (Postal Survey of Self-Assessed Health of MS Adults and their Significant Others) on a random sample of 251 adults with MS from the Milan area (mean age 42years, range 18-71years), and prospectively assessed changes in self-perceived health status over 11years. Participants completed the Multiple Sclerosis Quality-of-Life-54 (MSQOL-54) and a general/clinical questionnaire. We re-assessed the cohort in 2004 and 2010, sending the same questionnaires plus the Chicago Multiscale Depression Inventory. Results: There were 205 (86%) respondents in 2004, 171 (74%) in 2010; 28 (11%) died during the study. Severely impaired [self-determined Expanded Disability Status Scale (EDSS)>6.5] increased from 19% to 32%. One-fifth remained fully ambulatory (EDSS

KW - Depression

KW - Longitudinal study

KW - Multiple sclerosis

KW - Patient-reported outcomes

KW - Quality of life

UR - http://www.scopus.com/inward/record.url?scp=84875053808&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84875053808&partnerID=8YFLogxK

U2 - 10.1111/ene.12028

DO - 10.1111/ene.12028

M3 - Article

VL - 20

SP - 681

EP - 688

JO - European Journal of Neurology

JF - European Journal of Neurology

SN - 1351-5101

IS - 4

ER -