Abstract
Background and purpose: Few data are available on the health status of people with multiple sclerosis (PwMS) in the community. We assessed changes in self-perceived health status and health related quality of life of a community-based cohort of PwMS over a decade, and identified predictors of such changes. Methods: In 1999 we started the POSMOS study (Postal Survey of Self-Assessed Health of MS Adults and their Significant Others) on a random sample of 251 adults with MS from the Milan area (mean age 42years, range 18-71years), and prospectively assessed changes in self-perceived health status over 11years. Participants completed the Multiple Sclerosis Quality-of-Life-54 (MSQOL-54) and a general/clinical questionnaire. We re-assessed the cohort in 2004 and 2010, sending the same questionnaires plus the Chicago Multiscale Depression Inventory. Results: There were 205 (86%) respondents in 2004, 171 (74%) in 2010; 28 (11%) died during the study. Severely impaired [self-determined Expanded Disability Status Scale (EDSS)>6.5] increased from 19% to 32%. One-fifth remained fully ambulatory (EDSS
| Original language | English |
|---|---|
| Pages (from-to) | 681-688 |
| Number of pages | 8 |
| Journal | European Journal of Neurology |
| Volume | 20 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Apr 2013 |
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Keywords
- Depression
- Longitudinal study
- Multiple sclerosis
- Patient-reported outcomes
- Quality of life
ASJC Scopus subject areas
- Clinical Neurology
- Neurology
Cite this
Self-assessed health status changes in a community cohort of people with multiple sclerosis : 11years of follow-up. / Giordano, A.; Ferrari, G.; Radice, D.; Randi, G.; Bisanti, L.; Solari, A.
In: European Journal of Neurology, Vol. 20, No. 4, 04.2013, p. 681-688.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Self-assessed health status changes in a community cohort of people with multiple sclerosis
T2 - 11years of follow-up
AU - Giordano, A.
AU - Ferrari, G.
AU - Radice, D.
AU - Randi, G.
AU - Bisanti, L.
AU - Solari, A.
PY - 2013/4
Y1 - 2013/4
N2 - Background and purpose: Few data are available on the health status of people with multiple sclerosis (PwMS) in the community. We assessed changes in self-perceived health status and health related quality of life of a community-based cohort of PwMS over a decade, and identified predictors of such changes. Methods: In 1999 we started the POSMOS study (Postal Survey of Self-Assessed Health of MS Adults and their Significant Others) on a random sample of 251 adults with MS from the Milan area (mean age 42years, range 18-71years), and prospectively assessed changes in self-perceived health status over 11years. Participants completed the Multiple Sclerosis Quality-of-Life-54 (MSQOL-54) and a general/clinical questionnaire. We re-assessed the cohort in 2004 and 2010, sending the same questionnaires plus the Chicago Multiscale Depression Inventory. Results: There were 205 (86%) respondents in 2004, 171 (74%) in 2010; 28 (11%) died during the study. Severely impaired [self-determined Expanded Disability Status Scale (EDSS)>6.5] increased from 19% to 32%. One-fifth remained fully ambulatory (EDSS
AB - Background and purpose: Few data are available on the health status of people with multiple sclerosis (PwMS) in the community. We assessed changes in self-perceived health status and health related quality of life of a community-based cohort of PwMS over a decade, and identified predictors of such changes. Methods: In 1999 we started the POSMOS study (Postal Survey of Self-Assessed Health of MS Adults and their Significant Others) on a random sample of 251 adults with MS from the Milan area (mean age 42years, range 18-71years), and prospectively assessed changes in self-perceived health status over 11years. Participants completed the Multiple Sclerosis Quality-of-Life-54 (MSQOL-54) and a general/clinical questionnaire. We re-assessed the cohort in 2004 and 2010, sending the same questionnaires plus the Chicago Multiscale Depression Inventory. Results: There were 205 (86%) respondents in 2004, 171 (74%) in 2010; 28 (11%) died during the study. Severely impaired [self-determined Expanded Disability Status Scale (EDSS)>6.5] increased from 19% to 32%. One-fifth remained fully ambulatory (EDSS
KW - Depression
KW - Longitudinal study
KW - Multiple sclerosis
KW - Patient-reported outcomes
KW - Quality of life
UR - http://www.scopus.com/inward/record.url?scp=84875053808&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84875053808&partnerID=8YFLogxK
U2 - 10.1111/ene.12028
DO - 10.1111/ene.12028
M3 - Article
VL - 20
SP - 681
EP - 688
JO - European Journal of Neurology
JF - European Journal of Neurology
SN - 1351-5101
IS - 4
ER -