Self-disorders and clinical high risk for psychosis: An empirical study in help-seeking youth attending community mental health facilities

Andrea Raballo, Elena Pappagallo, Alice Dell Erba, Nella Lo Cascio, Martina Patane, Eva Gebhardt, Tommaso Boldrini, Laura Terzariol, Massimiliano Angelone, Alberto Trisolini, Paolo Girardi, Paolo Fiori Nastro

Research output: Contribution to journalArticle

Abstract

Anomalous subjective experiences involving an alteration of the basic sense of self (ie, Self-disorder [SD]) are emerging as a core marker of schizophrenia spectrum disorders with potential impact on current early detection strategies as well. In this study, we wished to field-test the prevalence of SD in a clinical sample of adolescent/young adult help-seekers at putative risk for psychosis attending standard community mental health facilities in Italy. Participants (n = 47), aged between 14 and 25, underwent extensive psychopathological evaluations with current semi-structured tools to assess Clinical High Risk (CHR) state (ie, Structured Interview for Prodromal Syndromes/Scale of Prodromal Symptoms [SIPS/SOPS], Schizophrenia Proneness Instrument-Adult/Child and Youth [SPI-A/CY]). SD aggregated in CHR subjects as compared to the non-CHR and revealed substantial association with sub-psychotic symptoms (SIPS), subjective experience of cognitive and cognitive-perceptual vulnerability (basic symptoms) and functional level (Global Assessment of functioning). Moreover, a combination of the 2 approaches (ie, CHR plus SD) enabled further closing-in on a subgroup of CHR with lower global functioning. The results confirm SD's relevance for the early profiling of youths at potential high risk for psychosis.

Original languageEnglish
Pages (from-to)926-932
Number of pages7
JournalSchizophrenia Bulletin
Volume42
Issue number4
DOIs
Publication statusPublished - 2016

Keywords

  • Basic symptoms
  • Clinical high risk
  • Positive symptoms
  • Prodrome
  • Psychosis
  • Self
  • Subjective experience

ASJC Scopus subject areas

  • Psychiatry and Mental health

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    Raballo, A., Pappagallo, E., Dell Erba, A., Lo Cascio, N., Patane, M., Gebhardt, E., Boldrini, T., Terzariol, L., Angelone, M., Trisolini, A., Girardi, P., & Nastro, P. F. (2016). Self-disorders and clinical high risk for psychosis: An empirical study in help-seeking youth attending community mental health facilities. Schizophrenia Bulletin, 42(4), 926-932. https://doi.org/10.1093/schbul/sbv223