Self-measurement of blood pressure in clinical trials and therapeutic applications

Thierry Denolle, Bernard Waeber, Sverre Kjeldsen, Gianfranco Parati, Marcus Wilson, Roland Asmar

Research output: Contribution to journalArticlepeer-review


Self-measurement of blood pressure (SMBP) is increasingly used to assess blood pressure outside the medical setting. A prerequisite for the wide use of SMBP is the availability of validated devices providing reliable readings when they are handled by patients. This is the case today with a number of fully automated oscillometric apparatuses. A major advantage of SMBP is the great number of readings, which is linked with high reproducibility. Given these advantages, one of the major indications for SMBP is the need for evaluation of antihypertensive treatment, either for individual patients in everyday practice or in clinical trials intended to characterize the effects of blood-pressure-lowering medications. In fact, SMBP is particularly helpful for evaluating resistant hypertension and detecting white-coat effect in patients exhibiting high office blood pressure under antihypertensive therapy. SMBP might also motivate the patient and improve his or her adherence to long-term treatment. Moreover, SMBP can be used as a sensitive technique for evaluating the effect of antihypertensive drugs in clinical trials; it increases the power of comparative trials, allowing one to study fewer patients or to detect smaller differences in blood pressure than would be possible with the office measurement. Therefore, SMBP can be regarded as a valuable technique for the follow-up of treated patients as well as for the assessment of antihypertensive drugs in clinical trials. 2000 Lippincott Williams and Wilkins.

Original languageEnglish
Pages (from-to)145-149
Number of pages5
JournalBlood Pressure Monitoring
Issue number2
Publication statusPublished - 2000


  • Home blood pressure
  • Hypertension
  • Self blood pressure
  • Treatment

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Self-measurement of blood pressure in clinical trials and therapeutic applications'. Together they form a unique fingerprint.

Cite this