Self-reported weight and height: Implications for left ventricular hypertrophy detection. An italian multi-center study

We examined the difference between self-reported and measured body size values and their impact on detection of left ventricular hypertrophy (LVH) by echocardiographic LV mass indexation. A total of 1963 subjects referred by their practitioners for routine echocardiographic examination to nine outpatient echocardiographic laboratories across Italy were included in the study. Left ventricular hypertrophy was defined according to two gender-specific criteria as: A) Left ventricular mass (LVM) index ≥49 g/h^2.7 in men and ≥45 g/h^2.7 in women; B) LVM index ≥125 g/m² in men and ≥110 g/m² in women. Prevalence of LVH was calculated by indexing LVM to both self-reported and measured anthropometric values. In the whole population, LVH tended to be underestimated by self-reported values by 5.4% according to criterion A (48.5% vs. 53.9%, p <0.001) and by 1.2% according to criterion B (29.6% vs. 30.8%, p <0.01); similar findings were observed in the hypertensive subgroup encompassing one-half of the sample. Underestimation of LVH was more pronounced in older patients than in younger patients: 8.6% vs. 3.2% (p <0.001) by criterion A, 3.1% vs. 0.1% (p <0.001) by criterion B, in women than in men (8.6% vs. 3.3% (p <0.001) by criterion A and 1.8% vs. 0.5% (p <0.01) by criterion B. In a sample of outpatients attending echocardiographic laboratories, LVH is misclassified when left ventricular mass is normalized to self-reported weight and height. The error is related to the clinical characteristics of patients and is more pronounced when LVM is normalized to height^2.7.