Sella turcica atypical teratoid/rhabdoid tumor complicated with lung metastasis in an adult female

Costanzo Moretti, Domenico Lupoi, Francesca Spasaro, Laura Chioma, Paola Di Giacinto, Martina Colicchia, Mario Frajoli, Renzo Mocini, Salvatore Ulisse, Manila Antonelli, Felice Giangaspero, Lucio Gnessi

Research output: Contribution to journalArticle

Abstract

Here we present the case of a 60-year-old woman with a rare sellar region atypical teratoid/rhabdoid tumor (AT/RT), complicated by lung metastasis and treated with neurosurgery, radiotherapy, and chemotherapy. The patient had recurrent headache associated with left cavernous sinus syndrome after a previous endonasal transsphenoidal resection for a presumptive pituitary macroadenoma. Pituitary magnetic resonance imaging showed a tumor regrowth in the original location with a haemorrhagic component involving the left cavernous sinus. A near complete transsphenoidal resection of the sellar mass was performed followed by 3 months of stereotactic radiotherapy. Because of a worsening of the general clinical conditions, respiratory failure, and asthenia, the patient underwent a contrast enhanced computer tomography of the whole body which showed the presence of lung metastasis. The histopathological diagnosis on samples from pituitary and lung tissues was AT/RT. The patient survived 30 months after diagnosis regardless chemotherapy. In the adult, the AT/RT should be considered as a possible rare, aggressive, and malignant neoplasm localized in the sella turcica.

Original languageEnglish
Pages (from-to)177-182
Number of pages6
JournalClinical Medicine Insights: Case Reports
Volume6
DOIs
Publication statusPublished - Nov 27 2013

Keywords

  • Atypical teratoid/rhabdoid tumor (AT/RT)
  • Lung
  • Metastasis
  • Sella turcica

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Moretti, C., Lupoi, D., Spasaro, F., Chioma, L., Di Giacinto, P., Colicchia, M., Frajoli, M., Mocini, R., Ulisse, S., Antonelli, M., Giangaspero, F., & Gnessi, L. (2013). Sella turcica atypical teratoid/rhabdoid tumor complicated with lung metastasis in an adult female. Clinical Medicine Insights: Case Reports, 6, 177-182. https://doi.org/10.4137/CCRep.S12834