Sensitive and ethnic skin

A need for special skin-care agents?

E. Berardesca, H. I. Maibach

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Sensitive skin is a complex problem with genetic, individual, environmental, occupational, and ethnic implications. Further work is needed to rank irritants and irritant reactions to classify sensitive skin on the basis of standard models. The development of topical products designed for sensitive and ethnic skin may be advisable to optimize drug activity with minimal side effects. The availability of transdermal systems for drug delivery highlights the problem. Occlusive transdermal patch systems for delivery of clonidine show sensitization rates of 34% in white women, 18% in white men, 14% in black women, and 8% in black men. Besides ethnic differences in transcutaneous penetration, individual and ethnic skin sensitivity may play an important role in determining both patient compliance and therapeutic efficacy of drugs and cosmetics; furthermore, a drug formulation considering skin physiology may prevent unwanted local and general adverse effects.

Original languageEnglish
Pages (from-to)89-92
Number of pages4
JournalDermatologic Clinics
Volume9
Issue number1
Publication statusPublished - 1991

Fingerprint

Skin Care
Skin
Irritants
Skin Physiological Phenomena
Transdermal Patch
Drug Compounding
Clonidine
Drug Delivery Systems
Patient Compliance
Cosmetics
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Dermatology

Cite this

Berardesca, E., & Maibach, H. I. (1991). Sensitive and ethnic skin: A need for special skin-care agents? Dermatologic Clinics, 9(1), 89-92.

Sensitive and ethnic skin : A need for special skin-care agents? / Berardesca, E.; Maibach, H. I.

In: Dermatologic Clinics, Vol. 9, No. 1, 1991, p. 89-92.

Research output: Contribution to journalArticle

Berardesca, E & Maibach, HI 1991, 'Sensitive and ethnic skin: A need for special skin-care agents?', Dermatologic Clinics, vol. 9, no. 1, pp. 89-92.
Berardesca, E. ; Maibach, H. I. / Sensitive and ethnic skin : A need for special skin-care agents?. In: Dermatologic Clinics. 1991 ; Vol. 9, No. 1. pp. 89-92.
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