Sensory (VEP, BAEP, SEP) and motor–evoked potentials, liquoral and magnetic resonance findings in multiple sclerosis

Paolo M. Rossini, F. Zarola, R. Floris, G. Bernardi, A. Perretti, L. Pelosi, G. Caruso, M. D. Caramia

Research output: Contribution to journalArticle

Abstract

In order to define the most suitable instrumental protocol for the diagnosis of multiple sclerosis (MS), 41 patients with definite (D = 14), probable (P = 14) and suspected (S = 13) MS were examined with CSF immunology, brain MRI and multimodal evoked potentials. The central motor tracts were also tested. The following alteration rates were found: MRI = 78%, CSF = 63.6%, VEP = 70.0%, median nerve SEP = 50%, peroneal nerve SEP = 68.0%, BAEPs = 35.7%, motor-evoked potentials (MEPs) = 74.0%. Altogether, EPs were abnormal in 90% of cases. Normal MRI with altered EPs were found in 22% of cases, whilst a normal EP battery with defective CSF or MRI findings were found in 7%. Twenty-six out of 27 patients with P or S forms were reclassified into a D one when considering EPs and MRI features.

Original languageEnglish
Pages (from-to)41-47
Number of pages7
JournalEuropean Neurology
Volume29
Issue number1
DOIs
Publication statusPublished - 1989

Keywords

  • Evoked potentials
  • Magnetic resonance
  • Multiple sclerosis

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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