Sentinel lymph node mapping opens a new perspective in the surgical management of early-stage breast cancer: A combined approach with vital blue dye lymphatic mapping and radioguided surgery

Giuseppe Canavese; Marco Gipponi; Alessandra Catturich; Carmine Di Somma; Carlo Vecchio; Francesco Rosato; Daniela Tomei; Ferdinando Cafiero; Luciano Moresco; Guido Nicolò; Franca Carli; Giuseppe Villa; Ferdinando Buffoni; Fausto Badellino

doi:10.1002/(SICI)1098-2388(199812)15:4<272::AID-SSU17>3.0.CO;2-I

Sentinel lymph node mapping opens a new perspective in the surgical management of early-stage breast cancer: A combined approach with vital blue dye lymphatic mapping and radioguided surgery

Giuseppe Canavese, Marco Gipponi, Alessandra Catturich, Carmine Di Somma, Carlo Vecchio, Francesco Rosato, Daniela Tomei, Ferdinando Cafiero, Luciano Moresco, Guido Nicolò, Franca Carli, Giuseppe Villa, Ferdinando Buffoni, Fausto Badellino

A.O.U. San Martino - IST, Istituto Nazionale Ricerca sul Cancro (GENOVA)

Research output: Contribution to journal › Article

Abstract

Recent studies have demonstrated the possibility of identifying the sentinel lymph node (sN) as a reliable predictor of axillary lymph node status in both cutaneous melanoma and breast cancer. However, some important issues need further definition: (1) optimization of the technique for intraoperative detection of the sN; (2) predictive value of the sN as regards axillary lymph node status, and (3) reliability of intraoperative histology of the sN. We report our experience in sN mapping in patients with Stage I- II breast cancer, with the aim of assessing: (1) the feasibility of lymphatic mapping with a combined approach (vital blue dye lymphatic mapping and radioguided surgery); (2) the agreement of the intraoperative histologic examination of the sN, by means of hematoxylin and eosin staining with final histology, and (3) the accuracy of sN histology as a predictor of axillary lymph node status.

Original language	English
Pages (from-to)	272-277
Number of pages	6
Journal	Seminars in Surgical Oncology
Volume	15
Issue number	4
DOIs	https://doi.org/10.1002/(SICI)1098-2388(199812)15:4<272::AID-SSU17>3.0.CO;2-I
Publication status	Published - 1998

Keywords

Axilla
Biopsy
Breast neoplasms
False negative reactions
Intraoperative period
Lymph node excision
Lymph nodes/radionuclide imaging/ pathology
Lymphatic metastasis
Melanoma
Neoplasm recurrence
Neoplasm staging
Predictive value of tests
Radioimmunodetection
Rosaniline dyes
Sensitivity and specificity
Staining
Technetium compounds

ASJC Scopus subject areas

Surgery
Oncology

Access to Document

10.1002/(SICI)1098-2388(199812)15:4<272::AID-SSU17>3.0.CO;2-I

Fingerprint Dive into the research topics of 'Sentinel lymph node mapping opens a new perspective in the surgical management of early-stage breast cancer: A combined approach with vital blue dye lymphatic mapping and radioguided surgery'. Together they form a unique fingerprint.

Cite this

Canavese, G., Gipponi, M., Catturich, A., Di Somma, C., Vecchio, C., Rosato, F., Tomei, D., Cafiero, F., Moresco, L., Nicolò, G., Carli, F., Villa, G., Buffoni, F., & Badellino, F. (1998). Sentinel lymph node mapping opens a new perspective in the surgical management of early-stage breast cancer: A combined approach with vital blue dye lymphatic mapping and radioguided surgery. Seminars in Surgical Oncology, 15(4), 272-277. https://doi.org/10.1002/(SICI)1098-2388(199812)15:4<272::AID-SSU17>3.0.CO;2-I

Sentinel lymph node mapping opens a new perspective in the surgical management of early-stage breast cancer : A combined approach with vital blue dye lymphatic mapping and radioguided surgery. / Canavese, Giuseppe; Gipponi, Marco; Catturich, Alessandra; Di Somma, Carmine; Vecchio, Carlo; Rosato, Francesco; Tomei, Daniela; Cafiero, Ferdinando; Moresco, Luciano; Nicolò, Guido; Carli, Franca; Villa, Giuseppe; Buffoni, Ferdinando; Badellino, Fausto.

In: Seminars in Surgical Oncology, Vol. 15, No. 4, 1998, p. 272-277.

Research output: Contribution to journal › Article

Canavese, G, Gipponi, M, Catturich, A, Di Somma, C, Vecchio, C, Rosato, F, Tomei, D, Cafiero, F, Moresco, L, Nicolò, G, Carli, F, Villa, G, Buffoni, F & Badellino, F 1998, 'Sentinel lymph node mapping opens a new perspective in the surgical management of early-stage breast cancer: A combined approach with vital blue dye lymphatic mapping and radioguided surgery', Seminars in Surgical Oncology, vol. 15, no. 4, pp. 272-277. https://doi.org/10.1002/(SICI)1098-2388(199812)15:4<272::AID-SSU17>3.0.CO;2-I

Canavese G, Gipponi M, Catturich A, Di Somma C, Vecchio C, Rosato F et al. Sentinel lymph node mapping opens a new perspective in the surgical management of early-stage breast cancer: A combined approach with vital blue dye lymphatic mapping and radioguided surgery. Seminars in Surgical Oncology. 1998;15(4):272-277. https://doi.org/10.1002/(SICI)1098-2388(199812)15:4<272::AID-SSU17>3.0.CO;2-I

Canavese, Giuseppe ; Gipponi, Marco ; Catturich, Alessandra ; Di Somma, Carmine ; Vecchio, Carlo ; Rosato, Francesco ; Tomei, Daniela ; Cafiero, Ferdinando ; Moresco, Luciano ; Nicolò, Guido ; Carli, Franca ; Villa, Giuseppe ; Buffoni, Ferdinando ; Badellino, Fausto. / Sentinel lymph node mapping opens a new perspective in the surgical management of early-stage breast cancer : A combined approach with vital blue dye lymphatic mapping and radioguided surgery. In: Seminars in Surgical Oncology. 1998 ; Vol. 15, No. 4. pp. 272-277.

@article{8b9058d965f6413abb7303164a1ee25b,

title = "Sentinel lymph node mapping opens a new perspective in the surgical management of early-stage breast cancer: A combined approach with vital blue dye lymphatic mapping and radioguided surgery",

abstract = "Recent studies have demonstrated the possibility of identifying the sentinel lymph node (sN) as a reliable predictor of axillary lymph node status in both cutaneous melanoma and breast cancer. However, some important issues need further definition: (1) optimization of the technique for intraoperative detection of the sN; (2) predictive value of the sN as regards axillary lymph node status, and (3) reliability of intraoperative histology of the sN. We report our experience in sN mapping in patients with Stage I- II breast cancer, with the aim of assessing: (1) the feasibility of lymphatic mapping with a combined approach (vital blue dye lymphatic mapping and radioguided surgery); (2) the agreement of the intraoperative histologic examination of the sN, by means of hematoxylin and eosin staining with final histology, and (3) the accuracy of sN histology as a predictor of axillary lymph node status.",

keywords = "Axilla, Biopsy, Breast neoplasms, False negative reactions, Intraoperative period, Lymph node excision, Lymph nodes/radionuclide imaging/ pathology, Lymphatic metastasis, Melanoma, Neoplasm recurrence, Neoplasm staging, Predictive value of tests, Radioimmunodetection, Rosaniline dyes, Sensitivity and specificity, Staining, Technetium compounds",

author = "Giuseppe Canavese and Marco Gipponi and Alessandra Catturich and {Di Somma}, Carmine and Carlo Vecchio and Francesco Rosato and Daniela Tomei and Ferdinando Cafiero and Luciano Moresco and Guido Nicol{\`o} and Franca Carli and Giuseppe Villa and Ferdinando Buffoni and Fausto Badellino",

year = "1998",

doi = "10.1002/(SICI)1098-2388(199812)15:4<272::AID-SSU17>3.0.CO;2-I",

language = "English",

volume = "15",

pages = "272--277",

journal = "Seminars in Surgical Oncology",

issn = "8756-0437",

publisher = "John Wiley and Sons Inc.",

number = "4",

}

TY - JOUR

T1 - Sentinel lymph node mapping opens a new perspective in the surgical management of early-stage breast cancer

T2 - A combined approach with vital blue dye lymphatic mapping and radioguided surgery

AU - Canavese, Giuseppe

AU - Gipponi, Marco

AU - Catturich, Alessandra

AU - Di Somma, Carmine

AU - Vecchio, Carlo

AU - Rosato, Francesco

AU - Tomei, Daniela

AU - Cafiero, Ferdinando

AU - Moresco, Luciano

AU - Nicolò, Guido

AU - Carli, Franca

AU - Villa, Giuseppe

AU - Buffoni, Ferdinando

AU - Badellino, Fausto

PY - 1998

Y1 - 1998

N2 - Recent studies have demonstrated the possibility of identifying the sentinel lymph node (sN) as a reliable predictor of axillary lymph node status in both cutaneous melanoma and breast cancer. However, some important issues need further definition: (1) optimization of the technique for intraoperative detection of the sN; (2) predictive value of the sN as regards axillary lymph node status, and (3) reliability of intraoperative histology of the sN. We report our experience in sN mapping in patients with Stage I- II breast cancer, with the aim of assessing: (1) the feasibility of lymphatic mapping with a combined approach (vital blue dye lymphatic mapping and radioguided surgery); (2) the agreement of the intraoperative histologic examination of the sN, by means of hematoxylin and eosin staining with final histology, and (3) the accuracy of sN histology as a predictor of axillary lymph node status.

AB - Recent studies have demonstrated the possibility of identifying the sentinel lymph node (sN) as a reliable predictor of axillary lymph node status in both cutaneous melanoma and breast cancer. However, some important issues need further definition: (1) optimization of the technique for intraoperative detection of the sN; (2) predictive value of the sN as regards axillary lymph node status, and (3) reliability of intraoperative histology of the sN. We report our experience in sN mapping in patients with Stage I- II breast cancer, with the aim of assessing: (1) the feasibility of lymphatic mapping with a combined approach (vital blue dye lymphatic mapping and radioguided surgery); (2) the agreement of the intraoperative histologic examination of the sN, by means of hematoxylin and eosin staining with final histology, and (3) the accuracy of sN histology as a predictor of axillary lymph node status.

KW - Axilla

KW - Biopsy

KW - Breast neoplasms

KW - False negative reactions

KW - Intraoperative period

KW - Lymph node excision

KW - Lymph nodes/radionuclide imaging/ pathology

KW - Lymphatic metastasis

KW - Melanoma

KW - Neoplasm recurrence

KW - Neoplasm staging

KW - Predictive value of tests

KW - Radioimmunodetection

KW - Rosaniline dyes

KW - Sensitivity and specificity

KW - Staining

KW - Technetium compounds

UR - http://www.scopus.com/inward/record.url?scp=7844247962&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=7844247962&partnerID=8YFLogxK

U2 - 10.1002/(SICI)1098-2388(199812)15:4<272::AID-SSU17>3.0.CO;2-I

DO - 10.1002/(SICI)1098-2388(199812)15:4<272::AID-SSU17>3.0.CO;2-I

M3 - Article

C2 - 9829386

AN - SCOPUS:7844247962

VL - 15

SP - 272

EP - 277

JO - Seminars in Surgical Oncology

JF - Seminars in Surgical Oncology

SN - 8756-0437

IS - 4

ER -