Abstract
Recent studies have demonstrated the possibility of identifying the sentinel lymph node (sN) as a reliable predictor of axillary lymph node status in both cutaneous melanoma and breast cancer. However, some important issues need further definition: (1) optimization of the technique for intraoperative detection of the sN; (2) predictive value of the sN as regards axillary lymph node status, and (3) reliability of intraoperative histology of the sN. We report our experience in sN mapping in patients with Stage I- II breast cancer, with the aim of assessing: (1) the feasibility of lymphatic mapping with a combined approach (vital blue dye lymphatic mapping and radioguided surgery); (2) the agreement of the intraoperative histologic examination of the sN, by means of hematoxylin and eosin staining with final histology, and (3) the accuracy of sN histology as a predictor of axillary lymph node status.
| Original language | English |
|---|---|
| Pages (from-to) | 272-277 |
| Number of pages | 6 |
| Journal | Seminars in Surgical Oncology |
| Volume | 15 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1998 |
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Keywords
- Axilla
- Biopsy
- Breast neoplasms
- False negative reactions
- Intraoperative period
- Lymph node excision
- Lymph nodes/radionuclide imaging/ pathology
- Lymphatic metastasis
- Melanoma
- Neoplasm recurrence
- Neoplasm staging
- Predictive value of tests
- Radioimmunodetection
- Rosaniline dyes
- Sensitivity and specificity
- Staining
- Technetium compounds
ASJC Scopus subject areas
- Surgery
- Oncology
Cite this
Sentinel lymph node mapping opens a new perspective in the surgical management of early-stage breast cancer : A combined approach with vital blue dye lymphatic mapping and radioguided surgery. / Canavese, Giuseppe; Gipponi, Marco; Catturich, Alessandra; Di Somma, Carmine; Vecchio, Carlo; Rosato, Francesco; Tomei, Daniela; Cafiero, Ferdinando; Moresco, Luciano; Nicolò, Guido; Carli, Franca; Villa, Giuseppe; Buffoni, Ferdinando; Badellino, Fausto.
In: Seminars in Surgical Oncology, Vol. 15, No. 4, 1998, p. 272-277.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Sentinel lymph node mapping opens a new perspective in the surgical management of early-stage breast cancer
T2 - A combined approach with vital blue dye lymphatic mapping and radioguided surgery
AU - Canavese, Giuseppe
AU - Gipponi, Marco
AU - Catturich, Alessandra
AU - Di Somma, Carmine
AU - Vecchio, Carlo
AU - Rosato, Francesco
AU - Tomei, Daniela
AU - Cafiero, Ferdinando
AU - Moresco, Luciano
AU - Nicolò, Guido
AU - Carli, Franca
AU - Villa, Giuseppe
AU - Buffoni, Ferdinando
AU - Badellino, Fausto
PY - 1998
Y1 - 1998
N2 - Recent studies have demonstrated the possibility of identifying the sentinel lymph node (sN) as a reliable predictor of axillary lymph node status in both cutaneous melanoma and breast cancer. However, some important issues need further definition: (1) optimization of the technique for intraoperative detection of the sN; (2) predictive value of the sN as regards axillary lymph node status, and (3) reliability of intraoperative histology of the sN. We report our experience in sN mapping in patients with Stage I- II breast cancer, with the aim of assessing: (1) the feasibility of lymphatic mapping with a combined approach (vital blue dye lymphatic mapping and radioguided surgery); (2) the agreement of the intraoperative histologic examination of the sN, by means of hematoxylin and eosin staining with final histology, and (3) the accuracy of sN histology as a predictor of axillary lymph node status.
AB - Recent studies have demonstrated the possibility of identifying the sentinel lymph node (sN) as a reliable predictor of axillary lymph node status in both cutaneous melanoma and breast cancer. However, some important issues need further definition: (1) optimization of the technique for intraoperative detection of the sN; (2) predictive value of the sN as regards axillary lymph node status, and (3) reliability of intraoperative histology of the sN. We report our experience in sN mapping in patients with Stage I- II breast cancer, with the aim of assessing: (1) the feasibility of lymphatic mapping with a combined approach (vital blue dye lymphatic mapping and radioguided surgery); (2) the agreement of the intraoperative histologic examination of the sN, by means of hematoxylin and eosin staining with final histology, and (3) the accuracy of sN histology as a predictor of axillary lymph node status.
KW - Axilla
KW - Biopsy
KW - Breast neoplasms
KW - False negative reactions
KW - Intraoperative period
KW - Lymph node excision
KW - Lymph nodes/radionuclide imaging/ pathology
KW - Lymphatic metastasis
KW - Melanoma
KW - Neoplasm recurrence
KW - Neoplasm staging
KW - Predictive value of tests
KW - Radioimmunodetection
KW - Rosaniline dyes
KW - Sensitivity and specificity
KW - Staining
KW - Technetium compounds
UR - http://www.scopus.com/inward/record.url?scp=7844247962&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=7844247962&partnerID=8YFLogxK
U2 - 10.1002/(SICI)1098-2388(199812)15:4<272::AID-SSU17>3.0.CO;2-I
DO - 10.1002/(SICI)1098-2388(199812)15:4<272::AID-SSU17>3.0.CO;2-I
M3 - Article
C2 - 9829386
AN - SCOPUS:7844247962
VL - 15
SP - 272
EP - 277
JO - Seminars in Surgical Oncology
JF - Seminars in Surgical Oncology
SN - 8756-0437
IS - 4
ER -