Sentinel node biopsy is not a standard procedure in ductal carcinoma in situ of the breast: The experience of the European institute of oncology on 854 patients in 10 years

Mattia Intra, Nicole Rotmensz, Paolo Veronesi, Marco Colleoni, Simona Iodice, Giovanni Paganelli, Giuseppe Viale, Umberto Veronesi

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE: The aim of this study is to assess the role of sentinel lymph node (SLN) biopsy in patients with pure ductal carcinoma in situ of the breast (DCIS) as a rationale for recommending the best managing option for the treatment of such patients in daily practice. SUMMARY BACKGROUND DATA: DCIS cannot give rise to axillary metastases by definition. Axillary dissection is therefore not indicated. The role of SLN biopsy in the management of DCIS has not yet been established. METHODS: From March 1996 to September 2006, 854 patients with pure DCIS underwent SLN biopsy at the European Institute of Oncology. Clinical and pathologic data were prospectively collected. When previous surgery or stereotactic biopsy had been performed elsewhere, all the histopathological preparations were reviewed. Patients with microinvasion were excluded from this investigation. Lymphatic mapping was performed using a radiocolloid technique. RESULTS: SLN metastases were detected in 12 (1.4%) DCIS patients. In 7 cases, only micrometastases (

Original languageEnglish
Pages (from-to)315-319
Number of pages5
JournalAnnals of Surgery
Volume247
Issue number2
DOIs
Publication statusPublished - Feb 2008

ASJC Scopus subject areas

  • Surgery

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