Separation of amino acid enentiomers by adding a chiral complex to the eluent

P. Masia, I. Nicoletti, M. Sinibaldi, D. Attanasio, A. Messina

Research output: Contribution to journalArticle

Abstract

Amino acid enantiomers are separated by reverse-phase chromatography with an optically active polyamine/Cu(II) complex in the mobile phase. The polyamine was obtained by reaction of ( - )-trans-1,2-diaminocyclohexane with ethylene glycol diglycidyl ether; the complex with copper(II) ions was used in the eluent. Separation factors are reported for ten amino acids and four barbiturates.

Original languageEnglish
Pages (from-to)145-150
Number of pages6
JournalAnalytica Chimica Acta
Volume204
Issue numberC
DOIs
Publication statusPublished - 1988

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Polyamines
amino acid
Amino Acids
Barbiturates
Enantiomers
Reverse-Phase Chromatography
Chromatography
ether
ethylene
chromatography
Copper
Ions
copper
ion
Quetol 651
1,2-cyclohexanediamine

ASJC Scopus subject areas

  • Biochemistry
  • Analytical Chemistry
  • Spectroscopy
  • Environmental Chemistry

Cite this

Separation of amino acid enentiomers by adding a chiral complex to the eluent. / Masia, P.; Nicoletti, I.; Sinibaldi, M.; Attanasio, D.; Messina, A.

In: Analytica Chimica Acta, Vol. 204, No. C, 1988, p. 145-150.

Research output: Contribution to journalArticle

Masia, P. ; Nicoletti, I. ; Sinibaldi, M. ; Attanasio, D. ; Messina, A. / Separation of amino acid enentiomers by adding a chiral complex to the eluent. In: Analytica Chimica Acta. 1988 ; Vol. 204, No. C. pp. 145-150.
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