SEPs study in infantile idiopathic epilepsies: Relevance of mid and long latency components

C. A. Tassinari, M. Blanco, R. Michelucci, G. Rubboli, F. Salvi, A. Forti, G. Ambrosetto, R. Plasmati

Research output: Chapter in Book/Report/Conference proceedingChapter


Sixty-four children with various forms of idiopathic infantile epilepsy (thirty two partial epilepsy with rolandic spikes) were studied with somatosensory evoked potentials (SEPs). No patients had neuroradiologic evidence of focal cerebral lesion and all had a normal neurological examination. Short latency SEPs were normal in latency and amplitude for all patients. In seventeen patients middle and long latency SEPs were of abnormally high amplitude. Amplitudes of up to 250 uV were recorded in these patients after stimulation of one or more limbs. These giant responses and normal long latency SEPs behaved similarly in their persistence in sleep, decreased in amplitude with increased frequency of stimulation, and disappearance after I.V. administration of diazepam. These results will be discussed in relation to: (1) De Marco's phenomenon of tactile spikes in EEG; (2) Abnormally large amplitude SEPs observed in other neurological conditions.

Original languageEnglish
Title of host publicationBollettino - Lega Italiana contro l'Epilessia
Number of pages2
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Clinical Neurology


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