Sequence versus phenylephrine assessment of the baroreflex gain in post-myocardial infarction patients

In this study we compared the baroreflex gain (BRG) measured by the phenylephrine technique (Phe-BRG) with BRG measured by the sequence technique (Seq-BRG) in 50 post-myocardial infarction patients (age: 52 ± 8 years. LVEF: 42 ± 12 %). Correlation analysis was performed to assess the degree of linear relationship between Phe-BRG and Seq-BRG. The agreement was investigated computing the bias and the limits of agreement of the two measures and of the percentage difference between the two measures. We found a moderate degree of linear association (correlation coefficient = 0.6 7). The bias was 2.2 ms/mmHg (p