Translated title of the contribution: Sequential therapy for ovarian cancer: utility of 'second look'

C. Mangioni, G. Bolis, N. Natale

Research output: Contribution to journalArticlepeer-review


The authors report their experience about second look in the longterm therapy of ovarian tumors, mainly of the advanced ones (stage 3). Two groups of 24 patients were compared: the first without clinical neoplastic evidence (complete responsiveness to the primary treatment) and the second with clinical signs of sure or probable persistent cancer. The results at second look, therapy and survival are presented. It is considered the role of second look laparoscopy correlated to second look laparotomy mainly for patients with stage 1C disease or a diffuse persistent tumor (endopelvic and abdominal carcinosi and/or diaphragmatic metastasis), for which the second look laparotomy was needless. Parameters usually considered in a longterm program of ovarian cancer therapy are compared. The extent of persistent cancer after primary therapy, the possibility and the characteristics of exeresis seem to be a parameter of prognosis of greater value than the clinical evaluation of cancer or its dimension (often uncertain and approximate evaluation). The importance of a careful description (size, dimension and removing possibility) of ovarian cancer extent during a longterm therapy points out the diagnostic, therapeutic and prognostic role of second look laparotomy after a careful selection on the basis of clinical and laparoscopic findings.

Translated title of the contributionSequential therapy for ovarian cancer: utility of 'second look'
Original languageItalian
Pages (from-to)205-214
Number of pages10
JournalAnnali di Ostetricia Ginecologia Medicina Perinatale
Issue number4
Publication statusPublished - 1976

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynaecology


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