Serial whole-brain N-acetylaspartate concentration in healthy young adults

D. J. Rigotti, M. Inglese, J. S. Babb, M. Rovaris, B. Benedetti, M. Filippi, R. I. Grossman, Oded Gonen

Research output: Contribution to journalArticle

Abstract

Although the concentration of N-acetylaspartate (NAA) is often used as a neuronal integrity marker, its normal temporal variations are not well documented. To assess them over the 1-2 year periods of typical clinical trials, the whole-brain NAA concentration was measured longitudinally, over 4 years, in a cohort of healthy young adults. No significant change (adjusted for both sex and age) was measured either interpersonally or intrapersonally over the entire duration of the study.

Original languageEnglish
Pages (from-to)1650-1651
Number of pages2
JournalAmerican Journal of Neuroradiology
Volume28
Issue number9
DOIs
Publication statusPublished - Oct 2007

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Young Adult
Brain
Clinical Trials
N-acetylaspartate

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Serial whole-brain N-acetylaspartate concentration in healthy young adults. / Rigotti, D. J.; Inglese, M.; Babb, J. S.; Rovaris, M.; Benedetti, B.; Filippi, M.; Grossman, R. I.; Gonen, Oded.

In: American Journal of Neuroradiology, Vol. 28, No. 9, 10.2007, p. 1650-1651.

Research output: Contribution to journalArticle

Rigotti, DJ, Inglese, M, Babb, JS, Rovaris, M, Benedetti, B, Filippi, M, Grossman, RI & Gonen, O 2007, 'Serial whole-brain N-acetylaspartate concentration in healthy young adults', American Journal of Neuroradiology, vol. 28, no. 9, pp. 1650-1651. https://doi.org/10.3174/ajnr.A0712
Rigotti, D. J. ; Inglese, M. ; Babb, J. S. ; Rovaris, M. ; Benedetti, B. ; Filippi, M. ; Grossman, R. I. ; Gonen, Oded. / Serial whole-brain N-acetylaspartate concentration in healthy young adults. In: American Journal of Neuroradiology. 2007 ; Vol. 28, No. 9. pp. 1650-1651.
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