Abstract
Laboratory evaluation of inflammation in rheumatic diseases is important both to quantify the extent of inflammation and to monitor disease activity. Improvement in CRP levels is an objective indication that a drug has produced a beneficial effect and thus may be useful to the physician for monitoring effects of therapy. Since CRP and ERS may be elevated in a number of conditions besides RA, a diagnosis of RA must be made before using CRP and ERS as a prognostic factor. The introduction of sensitive assays to quantitate many inflammatory-associated cytokines increased the interest in measuring these potent inflammatory mediators; in particular, IL-6 increases rapidly after inflammatory stimuli and serum level of this cytokine correlates with the severity and course of the disease process in rheumatoid arthritis.
| Original language | Italian |
|---|---|
| Pages (from-to) | 19-28 |
| Number of pages | 10 |
| Journal | Progressi in Reumatologia |
| Volume | 5 |
| Issue number | 1 |
| Publication status | Published - 2004 |
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ASJC Scopus subject areas
- Rheumatology
Cite this
Markers sierologici dell'infiammazione nelle malattie reumatiche. / Sarzi-Puttini, Pircarlo C.; Atzeni, F.
In: Progressi in Reumatologia, Vol. 5, No. 1, 2004, p. 19-28.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Markers sierologici dell'infiammazione nelle malattie reumatiche
AU - Sarzi-Puttini, Pircarlo C.
AU - Atzeni, F.
PY - 2004
Y1 - 2004
N2 - Laboratory evaluation of inflammation in rheumatic diseases is important both to quantify the extent of inflammation and to monitor disease activity. Improvement in CRP levels is an objective indication that a drug has produced a beneficial effect and thus may be useful to the physician for monitoring effects of therapy. Since CRP and ERS may be elevated in a number of conditions besides RA, a diagnosis of RA must be made before using CRP and ERS as a prognostic factor. The introduction of sensitive assays to quantitate many inflammatory-associated cytokines increased the interest in measuring these potent inflammatory mediators; in particular, IL-6 increases rapidly after inflammatory stimuli and serum level of this cytokine correlates with the severity and course of the disease process in rheumatoid arthritis.
AB - Laboratory evaluation of inflammation in rheumatic diseases is important both to quantify the extent of inflammation and to monitor disease activity. Improvement in CRP levels is an objective indication that a drug has produced a beneficial effect and thus may be useful to the physician for monitoring effects of therapy. Since CRP and ERS may be elevated in a number of conditions besides RA, a diagnosis of RA must be made before using CRP and ERS as a prognostic factor. The introduction of sensitive assays to quantitate many inflammatory-associated cytokines increased the interest in measuring these potent inflammatory mediators; in particular, IL-6 increases rapidly after inflammatory stimuli and serum level of this cytokine correlates with the severity and course of the disease process in rheumatoid arthritis.
KW - Acute phase proteins
KW - CRP
KW - Cytokines
KW - ESR
KW - Laboratory exams
UR - http://www.scopus.com/inward/record.url?scp=2142806749&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=2142806749&partnerID=8YFLogxK
M3 - Articolo
VL - 5
SP - 19
EP - 28
JO - Progressi in Reumatologia
JF - Progressi in Reumatologia
SN - 1129-8758
IS - 1
ER -