Laboratory evaluation of inflammation in rheumatic diseases is important both to quantify the extent of inflammation and to monitor disease activity. Improvement in CRP levels is an objective indication that a drug has produced a beneficial effect and thus may be useful to the physician for monitoring effects of therapy. Since CRP and ERS may be elevated in a number of conditions besides RA, a diagnosis of RA must be made before using CRP and ERS as a prognostic factor. The introduction of sensitive assays to quantitate many inflammatory-associated cytokines increased the interest in measuring these potent inflammatory mediators; in particular, IL-6 increases rapidly after inflammatory stimuli and serum level of this cytokine correlates with the severity and course of the disease process in rheumatoid arthritis.
|Translated title of the contribution||Serologic markers of inflammation in rheumatic diseases|
|Number of pages||10|
|Journal||Progressi in Reumatologia|
|Publication status||Published - 2004|
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