Seroprevalence and seroincidence of herpes simplex virus type 1 and herpes simplex virus type 2 infections in a cohort of adolescents in Italy

Barbara Suligoi, Arianna Torri, Gualtiero Grilli, Elisabetta Tanzi, Giorgio Palù, F. Boselli, R. Caputo, M. Cusini, S. Delia, G. Gentile, P. Martino, A. Volpi, V. Vullo

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: The objective of this study was to improve the knowledge on the epidemiology of herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) in Italy. Goal: The goal of this study was to study the seroincidence and seroprevalence of HSV-1 and HSV-2 infections among Italian adolescents. Study: We conducted a retrospective longitudinal study among 345 Italian adolescents tested for anti-HSV-1 and anti-HSV-2 on samples collected at 11 and 17 years of age. Results: At 11 years of age, the HSV-1 prevalence was 51.6% and the HSV-2 prevalence was 2.6%; when 17 years old, these rates increased to 61.4% and 4.9%, respectively. The HSV-1 incidence was 1.6 per 100 person-years and was higher among females. The HSV-2 incidence was 0.4 per 100 person-years with no gender differences. Conclusion: HSV-1 is apparently widespread among Italian adolescents, whereas HSV-2 is limited. These data are of paramount importance when considering that HSV-1 can cause genital herpes and that HSV-2 plays a role in HIV transmission.

Original languageEnglish
Pages (from-to)608-610
Number of pages3
JournalSexually Transmitted Diseases
Volume31
Issue number10
DOIs
Publication statusPublished - Oct 2004

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)

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