Serotonin in allergic rhinitis: A possible role for behavioural symptoms

Giorgio Ciprandi, Mara De Amici, Mariangela Tosca, Roberta Alesina, Gianluigi Marseglia, Dietmar Fuchs

Research output: Contribution to journalArticlepeer-review


Allergic rhinitis (AR) is a very frequent disease which is not only characterized by nasal symptoms, but also with behavioural changes. This study evaluated the serum serotonin levels in patients with pollen-induced AR during and outside the pollen season. One-hundred-two (56 females, 46 males, median age: 28.7 years) were included in this study: 56 with seasonal AR (SAR) evaluated outside the pollen season and so without allergic inflammation and symptoms, and 46 with SAR evaluated during the pollen season with symptoms. Blood specimens were collected to assess serum concentrations of serotonin and to compare results to scores of a Quality of Life (QoL) questionnaire which was performed in all subjects. Serotonin serum concentrations were higher in AR patients out of pollen season than in (p

Original languageEnglish
Pages (from-to)183-188
Number of pages6
JournalIranian Journal of Allergy, Asthma and Immunology
Issue number3
Publication statusPublished - Sep 2011


  • Allergic rhinitis
  • Behavioral symptoms
  • Pollen allergen exposure
  • Serotonin
  • Serum

ASJC Scopus subject areas

  • Immunology and Allergy


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