Studio del trasporto di serotonina nelle piastrine di pazienti in eta evolutiva con disturbi psicopatologici

B. Begni; M. Molteni; M. Nobile; A. Frigerio; C. Ferrarese

Studio del trasporto di serotonina nelle piastrine di pazienti in eta evolutiva con disturbi psicopatologici

Translated title of the contribution: Serotonin uptake in platelets from child neuropsychiatric patients

B. Begni, M. Molteni, M. Nobile, A. Frigerio, C. Ferrarese

Istituto "Eugenio Medea" - Associazione La Nostra Famiglia

Research output: Contribution to journal › Article › peer-review

Abstract

Serotonin uptake abnormalities have been widely described in depressed adult patients. However, few studies analyzed this peripheral marker of serotonergic system in child neuropsychiatric disorders, despite the clinical use of serotonin uptake inhibitors in these syndromes. In this preliminary study, we investigated possible modifications of serotonin uptake in platelets from 34 child neuropsychiatric patients, aged 7-16, devided, according to the ICD10 classification, into the following cathegories: Attention Deficit Hyperactivity Disorder (ADHD), child autism, anxious syndromes, dysthymia. 10 normal age and sex related children were used as controls. Serotonin uptake was determined in fresh platelet preparations, using [³H]serotonin, according to the method of Arora and Meltzer. Platelet serotonin uptake was decreased by 60% (p

Translated title of the contribution	Serotonin uptake in platelets from child neuropsychiatric patients
Original language	Italian
Pages (from-to)	13-19
Number of pages	7
Journal	SAGGI - Neuropsicologia Infantile Psicopedagogia Riabilitazione
Volume	24
Issue number	1
Publication status	Published - 1998

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Neuroscience(all)
Psychology(all)

Fingerprint Dive into the research topics of 'Serotonin uptake in platelets from child neuropsychiatric patients'. Together they form a unique fingerprint.

Cite this

@article{99a9eb8c4b074dd9823121b91103b219,

title = "Studio del trasporto di serotonina nelle piastrine di pazienti in eta evolutiva con disturbi psicopatologici",

abstract = "Serotonin uptake abnormalities have been widely described in depressed adult patients. However, few studies analyzed this peripheral marker of serotonergic system in child neuropsychiatric disorders, despite the clinical use of serotonin uptake inhibitors in these syndromes. In this preliminary study, we investigated possible modifications of serotonin uptake in platelets from 34 child neuropsychiatric patients, aged 7-16, devided, according to the ICD10 classification, into the following cathegories: Attention Deficit Hyperactivity Disorder (ADHD), child autism, anxious syndromes, dysthymia. 10 normal age and sex related children were used as controls. Serotonin uptake was determined in fresh platelet preparations, using [3H]serotonin, according to the method of Arora and Meltzer. Platelet serotonin uptake was decreased by 60% (p",

keywords = "Depression, Platelets, Serotonin",

author = "B. Begni and M. Molteni and M. Nobile and A. Frigerio and C. Ferrarese",

year = "1998",

language = "Italian",

volume = "24",

pages = "13--19",

journal = "SAGGI - Child Development and Disabilities",

issn = "0390-5179",

publisher = "Associazione La Nostra Famiglia",

number = "1",

}

TY - JOUR

T1 - Studio del trasporto di serotonina nelle piastrine di pazienti in eta evolutiva con disturbi psicopatologici

AU - Begni, B.

AU - Molteni, M.

AU - Nobile, M.

AU - Frigerio, A.

AU - Ferrarese, C.

PY - 1998

Y1 - 1998

N2 - Serotonin uptake abnormalities have been widely described in depressed adult patients. However, few studies analyzed this peripheral marker of serotonergic system in child neuropsychiatric disorders, despite the clinical use of serotonin uptake inhibitors in these syndromes. In this preliminary study, we investigated possible modifications of serotonin uptake in platelets from 34 child neuropsychiatric patients, aged 7-16, devided, according to the ICD10 classification, into the following cathegories: Attention Deficit Hyperactivity Disorder (ADHD), child autism, anxious syndromes, dysthymia. 10 normal age and sex related children were used as controls. Serotonin uptake was determined in fresh platelet preparations, using [3H]serotonin, according to the method of Arora and Meltzer. Platelet serotonin uptake was decreased by 60% (p

AB - Serotonin uptake abnormalities have been widely described in depressed adult patients. However, few studies analyzed this peripheral marker of serotonergic system in child neuropsychiatric disorders, despite the clinical use of serotonin uptake inhibitors in these syndromes. In this preliminary study, we investigated possible modifications of serotonin uptake in platelets from 34 child neuropsychiatric patients, aged 7-16, devided, according to the ICD10 classification, into the following cathegories: Attention Deficit Hyperactivity Disorder (ADHD), child autism, anxious syndromes, dysthymia. 10 normal age and sex related children were used as controls. Serotonin uptake was determined in fresh platelet preparations, using [3H]serotonin, according to the method of Arora and Meltzer. Platelet serotonin uptake was decreased by 60% (p

KW - Depression

KW - Platelets

KW - Serotonin

UR - http://www.scopus.com/inward/record.url?scp=0031867102&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031867102&partnerID=8YFLogxK

M3 - Articolo

AN - SCOPUS:0031867102

VL - 24

SP - 13

EP - 19

JO - SAGGI - Child Development and Disabilities

JF - SAGGI - Child Development and Disabilities

SN - 0390-5179

IS - 1

ER -

Studio del trasporto di serotonina nelle piastrine di pazienti in eta evolutiva con disturbi psicopatologici

Abstract

ASJC Scopus subject areas

Other files and links

Cite this