Abstract
Serotonin uptake abnormalities have been widely described in depressed adult patients. However, few studies analyzed this peripheral marker of serotonergic system in child neuropsychiatric disorders, despite the clinical use of serotonin uptake inhibitors in these syndromes. In this preliminary study, we investigated possible modifications of serotonin uptake in platelets from 34 child neuropsychiatric patients, aged 7-16, devided, according to the ICD10 classification, into the following cathegories: Attention Deficit Hyperactivity Disorder (ADHD), child autism, anxious syndromes, dysthymia. 10 normal age and sex related children were used as controls. Serotonin uptake was determined in fresh platelet preparations, using [3H]serotonin, according to the method of Arora and Meltzer. Platelet serotonin uptake was decreased by 60% (p
| Original language | Italian |
|---|---|
| Pages (from-to) | 13-19 |
| Number of pages | 7 |
| Journal | SAGGI - Neuropsicologia Infantile Psicopedagogia Riabilitazione |
| Volume | 24 |
| Issue number | 1 |
| Publication status | Published - 1998 |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Neuroscience(all)
- Psychology(all)
Cite this
Studio del trasporto di serotonina nelle piastrine di pazienti in eta evolutiva con disturbi psicopatologici. / Begni, B.; Molteni, M.; Nobile, M.; Frigerio, A.; Ferrarese, C.
In: SAGGI - Neuropsicologia Infantile Psicopedagogia Riabilitazione, Vol. 24, No. 1, 1998, p. 13-19.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Studio del trasporto di serotonina nelle piastrine di pazienti in eta evolutiva con disturbi psicopatologici
AU - Begni, B.
AU - Molteni, M.
AU - Nobile, M.
AU - Frigerio, A.
AU - Ferrarese, C.
PY - 1998
Y1 - 1998
N2 - Serotonin uptake abnormalities have been widely described in depressed adult patients. However, few studies analyzed this peripheral marker of serotonergic system in child neuropsychiatric disorders, despite the clinical use of serotonin uptake inhibitors in these syndromes. In this preliminary study, we investigated possible modifications of serotonin uptake in platelets from 34 child neuropsychiatric patients, aged 7-16, devided, according to the ICD10 classification, into the following cathegories: Attention Deficit Hyperactivity Disorder (ADHD), child autism, anxious syndromes, dysthymia. 10 normal age and sex related children were used as controls. Serotonin uptake was determined in fresh platelet preparations, using [3H]serotonin, according to the method of Arora and Meltzer. Platelet serotonin uptake was decreased by 60% (p
AB - Serotonin uptake abnormalities have been widely described in depressed adult patients. However, few studies analyzed this peripheral marker of serotonergic system in child neuropsychiatric disorders, despite the clinical use of serotonin uptake inhibitors in these syndromes. In this preliminary study, we investigated possible modifications of serotonin uptake in platelets from 34 child neuropsychiatric patients, aged 7-16, devided, according to the ICD10 classification, into the following cathegories: Attention Deficit Hyperactivity Disorder (ADHD), child autism, anxious syndromes, dysthymia. 10 normal age and sex related children were used as controls. Serotonin uptake was determined in fresh platelet preparations, using [3H]serotonin, according to the method of Arora and Meltzer. Platelet serotonin uptake was decreased by 60% (p
KW - Depression
KW - Platelets
KW - Serotonin
UR - http://www.scopus.com/inward/record.url?scp=0031867102&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031867102&partnerID=8YFLogxK
M3 - Articolo
AN - SCOPUS:0031867102
VL - 24
SP - 13
EP - 19
JO - SAGGI - Child Development and Disabilities
JF - SAGGI - Child Development and Disabilities
SN - 0390-5179
IS - 1
ER -