Sertraline in the treatment of depressive disorders in patients with Parkinson's disease

Silvia Marino, Edoardo Sessa, Giuseppe Di Lorenzo, Giuseppina Digangi, Antonella Alagna, Placido Bramanti, Paolo Di Bella

Research output: Contribution to journalArticlepeer-review

Abstract

We studied 54 idiopathic Parkinson's disease (PD) patients with depressive disorders (DD) to compare the efficacy and the effect of treatment with sertraline in the usual formulation and in the liquid oral concentrate (LOC) formulation. After 6 months of sertraline treatment, the Hamilton Depression Rating Scale and the Montgomery and Asberg Depression Rating Scale showed a decrement (p <0.001, for both formulations). Parkinson's Disease Questionnaire scores improved (p <0.005 for usual formulation and p

Original languageEnglish
Pages (from-to)391-395
Number of pages5
JournalNeurological Sciences
Volume29
Issue number6
DOIs
Publication statusPublished - 2008

Keywords

  • Depressive disorders
  • Parkinson's disease
  • Quality of life
  • Sertraline

ASJC Scopus subject areas

  • Dermatology
  • Clinical Neurology
  • Psychiatry and Mental health

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