Abstract
Growth hormone (GH) plays an important role on both bone and collagen metabolism via systemic insulin-like growth factors (IGF) production or directly by stimulating either the differentiation of precursor cells or the local production of growth factors. In this study we evaluated serum amino- terminal propeptide of type III procollagen (PIIINP) levels, specific and reliable marker of collagen synthesis, in a group of patients with acromegaly (4M, 3F, age range: 29-63 yrs) before and 2, 6 and 9 months after transnasosphenoidal pituitary adenomectomy. In active acromegaly (GH: 23.6±7.6 ng/ml, IGF-I: 140.5±18 nmol/L), mean PIIINP levels were significantly higher than in controls (8.3±1.1 vs 3.3±0.2 ng/ml, p
| Original language | English |
|---|---|
| Pages (from-to) | 79-83 |
| Number of pages | 5 |
| Journal | European Journal of Internal Medicine, Supplement |
| Volume | 4 |
| Issue number | 1 |
| Publication status | Published - 1993 |
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ASJC Scopus subject areas
- Medicine(all)
- Internal Medicine
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Serum amino-terminal propeptide of type III procollagen (PIIINP) levels in patients with acromegaly before and after pituitary adenomectomy. / Sartorio, A.; Monzani, M.; Conti, A.; Casati, G.; Faglia, G.
In: European Journal of Internal Medicine, Supplement, Vol. 4, No. 1, 1993, p. 79-83.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Serum amino-terminal propeptide of type III procollagen (PIIINP) levels in patients with acromegaly before and after pituitary adenomectomy
AU - Sartorio, A.
AU - Monzani, M.
AU - Conti, A.
AU - Casati, G.
AU - Faglia, G.
PY - 1993
Y1 - 1993
N2 - Growth hormone (GH) plays an important role on both bone and collagen metabolism via systemic insulin-like growth factors (IGF) production or directly by stimulating either the differentiation of precursor cells or the local production of growth factors. In this study we evaluated serum amino- terminal propeptide of type III procollagen (PIIINP) levels, specific and reliable marker of collagen synthesis, in a group of patients with acromegaly (4M, 3F, age range: 29-63 yrs) before and 2, 6 and 9 months after transnasosphenoidal pituitary adenomectomy. In active acromegaly (GH: 23.6±7.6 ng/ml, IGF-I: 140.5±18 nmol/L), mean PIIINP levels were significantly higher than in controls (8.3±1.1 vs 3.3±0.2 ng/ml, p
AB - Growth hormone (GH) plays an important role on both bone and collagen metabolism via systemic insulin-like growth factors (IGF) production or directly by stimulating either the differentiation of precursor cells or the local production of growth factors. In this study we evaluated serum amino- terminal propeptide of type III procollagen (PIIINP) levels, specific and reliable marker of collagen synthesis, in a group of patients with acromegaly (4M, 3F, age range: 29-63 yrs) before and 2, 6 and 9 months after transnasosphenoidal pituitary adenomectomy. In active acromegaly (GH: 23.6±7.6 ng/ml, IGF-I: 140.5±18 nmol/L), mean PIIINP levels were significantly higher than in controls (8.3±1.1 vs 3.3±0.2 ng/ml, p
UR - http://www.scopus.com/inward/record.url?scp=0027438138&partnerID=8YFLogxK
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M3 - Article
AN - SCOPUS:0027438138
VL - 4
SP - 79
EP - 83
JO - European Journal of Internal Medicine, Supplement
JF - European Journal of Internal Medicine, Supplement
SN - 1121-8967
IS - 1
ER -