Serum Ca-125 concentrations in endometriosis

L. Fedele, L. Arcaini, P. Vercellini, M. Marchini, A. Baglioni, S. Bianchi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Serum Ca-125 levels were measured in 154 patients undergoing laparoscopy or laparotomy for infertility and/or pelvic pain. Pelvic endometriosis at various stages was observed in 102 of the patients, and 52 had a visually normal pelvis and served as a control group. We found a significantly higher mean serum Ca-125 concentration in the patients with stages III and IV endometriosis compared with the controls (P <0.001) whereas in the patients with stages I and II disease the mean antigen level was comparable to that of the control group. Considering its low sensitivity (14.7%) the usefulness of serum Ca-125 measurements as an initial diagnostic test for endometriosis is scanty. On the contrary, because of its elevated specificity (100%), this test may be useful in indicating early surgical exploration of the pelvis in cases of infertility and/or dysmenorrhea which are associated with high values of Ca-125.

Original languageEnglish
Pages (from-to)137-139
Number of pages3
JournalActa Europaea Fertilitatis
Volume20
Issue number3
Publication statusPublished - 1989

Fingerprint

Endometriosis
Serum
Pelvis
Infertility
Dysmenorrhea
Control Groups
Pelvic Pain
Routine Diagnostic Tests
Laparoscopy
Laparotomy
Antigens

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Serum Ca-125 concentrations in endometriosis. / Fedele, L.; Arcaini, L.; Vercellini, P.; Marchini, M.; Baglioni, A.; Bianchi, S.

In: Acta Europaea Fertilitatis, Vol. 20, No. 3, 1989, p. 137-139.

Research output: Contribution to journalArticle

Fedele, L, Arcaini, L, Vercellini, P, Marchini, M, Baglioni, A & Bianchi, S 1989, 'Serum Ca-125 concentrations in endometriosis', Acta Europaea Fertilitatis, vol. 20, no. 3, pp. 137-139.
Fedele, L. ; Arcaini, L. ; Vercellini, P. ; Marchini, M. ; Baglioni, A. ; Bianchi, S. / Serum Ca-125 concentrations in endometriosis. In: Acta Europaea Fertilitatis. 1989 ; Vol. 20, No. 3. pp. 137-139.
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AU - Bianchi, S.

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