Serum IL-9 levels depend on allergen exposure: Preliminary study

Giorgio Ciprandi, Mara De Amici, Anna Maria Castellazzi, Maria Angela Tosca, Gianluigi Marseglia

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: Th9 is a new T cell subset characterized by interleukin 9 (IL-9) production. Serum IL-9 levels are related to symptom severity in patients with allergic rhinitis (AR). This study aimed at investigating whether IL-9 may depend on allergen exposure. Methods: 35 AR patients (16 males, mean age 33.2 years) with monosensitization to Parietaria were studied when symptomatic; 38 AR patients (22 males, mean age 30.9 years) with monosensitization to birch were recruited at the same time, but were symptom free. Serum IL-9 was assayed in all patients. Results: Patients with Parietaria allergy and exposed to allergen had higher serum IL-9 levels than patients with birch allergy and not exposed to allergen (p <0.05). Conclusions: This preliminary study shows that serum IL-9 levels may depend on allergen exposure: symptomatic patients with pollen-induced AR, evaluated during the pollen season, have higher values than patients studied outside the pollen season and without symptoms.

Original languageEnglish
Pages (from-to)246-248
Number of pages3
JournalInternational Archives of Allergy and Immunology
Volume154
Issue number3
DOIs
Publication statusPublished - Feb 2011

Fingerprint

Interleukin-9
Allergens
Serum
Parietaria
Pollen
Betula
Hypersensitivity
T-Lymphocyte Subsets
Allergic Rhinitis

Keywords

  • Allergen exposure
  • Allergic rhinitis
  • Pollen allergy
  • Pollen season
  • Serum interleukin 9

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Serum IL-9 levels depend on allergen exposure : Preliminary study. / Ciprandi, Giorgio; De Amici, Mara; Castellazzi, Anna Maria; Tosca, Maria Angela; Marseglia, Gianluigi.

In: International Archives of Allergy and Immunology, Vol. 154, No. 3, 02.2011, p. 246-248.

Research output: Contribution to journalArticle

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AU - Marseglia, Gianluigi

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