Serum leptin levels are not influenced by arginine and insulin infusion and by acute changes of GH

Giorgio Radetti, C. Tinelli, C. Paganini, M. Draghi, D. Scarcella, E. Bozzola, G. Aimaretti, G. Rondini, L. Tatò

Research output: Contribution to journalArticle

Abstract

The aim of this study was to evaluate the relationship between GH and leptin in a group of short children and adolescents. Leptin and GH serum levels were measured before and during pharmacological stimulation tests (arginine and insulin) in a group of 45 children (30 male, 15 female), mean age 8.6±3.9 yr, affected by idiopathic isolated GH deficiency (GHD), and in a group of 27 children (15 male, 12 female), age 10.9±3.3 yr, with constitutional growth delay. Results showed that basal and peak leptin levels as well as the AUC were significantly higher in GHD patients compared to controls (p

Original languageEnglish
Pages (from-to)769-772
Number of pages4
JournalJournal of Endocrinological Investigation
Volume25
Issue number9
Publication statusPublished - Oct 2002

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Keywords

  • Arginine infusion
  • GH
  • GH deficiency
  • Insulin-induced hypoglycaemia
  • Leptin

ASJC Scopus subject areas

  • Endocrinology

Cite this

Radetti, G., Tinelli, C., Paganini, C., Draghi, M., Scarcella, D., Bozzola, E., Aimaretti, G., Rondini, G., & Tatò, L. (2002). Serum leptin levels are not influenced by arginine and insulin infusion and by acute changes of GH. Journal of Endocrinological Investigation, 25(9), 769-772.