Abstract
Background/Aim: Serum levels of leptin, the adipocyte-derived hormone regulating food intake and energy expenditure in mammals, have been found to be increased in cirrhotic patients. The aim of the present study was to investigate leptin serum level in relation to anthropometric features and liver function in patients with viral chronic hepatitis or liver cirrhosis. Methods: Serum leptin levels were determined by radioimmunoassay in 30 male and 10 female patients with chronic hepatitis, in 42 male and 10 female patients with liver cirrhosis, and in four respective control groups. Liver function was evaluated by the monoethylglycinexylidide formation test. Body mass index and body fat mass were estimated by weight, height and skinfold thickness measurements. Results: Compared with controls, absolute serum leptin levels were significantly (p
| Original language | English |
|---|---|
| Pages (from-to) | 33-37 |
| Number of pages | 5 |
| Journal | Journal of Hepatology |
| Volume | 33 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jul 2000 |
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Keywords
- Chronic viral hepatitis
- Leptin
- Liver cirrhosis
- MEGX30
ASJC Scopus subject areas
- Gastroenterology
Cite this
Serum leptin levels in patients with viral chronic hepatitis or liver cirrhosis. / Testa, Roberto; Franceschini, Roberto; Giannini, Edoardo; Cataldi, Angelo; Botta, Federica; Fasoli, Alberto; Tenerelli, Pasquale; Rolandi, Ermanno; Barreca, Tommaso.
In: Journal of Hepatology, Vol. 33, No. 1, 07.2000, p. 33-37.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Serum leptin levels in patients with viral chronic hepatitis or liver cirrhosis
AU - Testa, Roberto
AU - Franceschini, Roberto
AU - Giannini, Edoardo
AU - Cataldi, Angelo
AU - Botta, Federica
AU - Fasoli, Alberto
AU - Tenerelli, Pasquale
AU - Rolandi, Ermanno
AU - Barreca, Tommaso
PY - 2000/7
Y1 - 2000/7
N2 - Background/Aim: Serum levels of leptin, the adipocyte-derived hormone regulating food intake and energy expenditure in mammals, have been found to be increased in cirrhotic patients. The aim of the present study was to investigate leptin serum level in relation to anthropometric features and liver function in patients with viral chronic hepatitis or liver cirrhosis. Methods: Serum leptin levels were determined by radioimmunoassay in 30 male and 10 female patients with chronic hepatitis, in 42 male and 10 female patients with liver cirrhosis, and in four respective control groups. Liver function was evaluated by the monoethylglycinexylidide formation test. Body mass index and body fat mass were estimated by weight, height and skinfold thickness measurements. Results: Compared with controls, absolute serum leptin levels were significantly (p
AB - Background/Aim: Serum levels of leptin, the adipocyte-derived hormone regulating food intake and energy expenditure in mammals, have been found to be increased in cirrhotic patients. The aim of the present study was to investigate leptin serum level in relation to anthropometric features and liver function in patients with viral chronic hepatitis or liver cirrhosis. Methods: Serum leptin levels were determined by radioimmunoassay in 30 male and 10 female patients with chronic hepatitis, in 42 male and 10 female patients with liver cirrhosis, and in four respective control groups. Liver function was evaluated by the monoethylglycinexylidide formation test. Body mass index and body fat mass were estimated by weight, height and skinfold thickness measurements. Results: Compared with controls, absolute serum leptin levels were significantly (p
KW - Chronic viral hepatitis
KW - Leptin
KW - Liver cirrhosis
KW - MEGX30
UR - http://www.scopus.com/inward/record.url?scp=0033943527&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033943527&partnerID=8YFLogxK
U2 - 10.1016/S0168-8278(00)80156-7
DO - 10.1016/S0168-8278(00)80156-7
M3 - Article
C2 - 10905583
AN - SCOPUS:0033943527
VL - 33
SP - 33
EP - 37
JO - Journal of Hepatology
JF - Journal of Hepatology
SN - 0168-8278
IS - 1
ER -