Serum leptin levels in patients with viral chronic hepatitis or liver cirrhosis

Roberto Testa, Roberto Franceschini, Edoardo Giannini, Angelo Cataldi, Federica Botta, Alberto Fasoli, Pasquale Tenerelli, Ermanno Rolandi, Tommaso Barreca

Research output: Contribution to journalArticle

92 Citations (Scopus)

Abstract

Background/Aim: Serum levels of leptin, the adipocyte-derived hormone regulating food intake and energy expenditure in mammals, have been found to be increased in cirrhotic patients. The aim of the present study was to investigate leptin serum level in relation to anthropometric features and liver function in patients with viral chronic hepatitis or liver cirrhosis. Methods: Serum leptin levels were determined by radioimmunoassay in 30 male and 10 female patients with chronic hepatitis, in 42 male and 10 female patients with liver cirrhosis, and in four respective control groups. Liver function was evaluated by the monoethylglycinexylidide formation test. Body mass index and body fat mass were estimated by weight, height and skinfold thickness measurements. Results: Compared with controls, absolute serum leptin levels were significantly (p

Original languageEnglish
Pages (from-to)33-37
Number of pages5
JournalJournal of Hepatology
Volume33
Issue number1
DOIs
Publication statusPublished - Jul 2000

Fingerprint

Chronic Hepatitis
Leptin
Liver Cirrhosis
Serum
monoethylglycinexylidide
Skinfold Thickness
Liver
Adipocytes
Energy Metabolism
Radioimmunoassay
Adipose Tissue
Mammals
Body Mass Index
Eating
Hormones
Weights and Measures
Control Groups

Keywords

  • Chronic viral hepatitis
  • Leptin
  • Liver cirrhosis
  • MEGX30

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Serum leptin levels in patients with viral chronic hepatitis or liver cirrhosis. / Testa, Roberto; Franceschini, Roberto; Giannini, Edoardo; Cataldi, Angelo; Botta, Federica; Fasoli, Alberto; Tenerelli, Pasquale; Rolandi, Ermanno; Barreca, Tommaso.

In: Journal of Hepatology, Vol. 33, No. 1, 07.2000, p. 33-37.

Research output: Contribution to journalArticle

Testa, R, Franceschini, R, Giannini, E, Cataldi, A, Botta, F, Fasoli, A, Tenerelli, P, Rolandi, E & Barreca, T 2000, 'Serum leptin levels in patients with viral chronic hepatitis or liver cirrhosis', Journal of Hepatology, vol. 33, no. 1, pp. 33-37. https://doi.org/10.1016/S0168-8278(00)80156-7
Testa, Roberto ; Franceschini, Roberto ; Giannini, Edoardo ; Cataldi, Angelo ; Botta, Federica ; Fasoli, Alberto ; Tenerelli, Pasquale ; Rolandi, Ermanno ; Barreca, Tommaso. / Serum leptin levels in patients with viral chronic hepatitis or liver cirrhosis. In: Journal of Hepatology. 2000 ; Vol. 33, No. 1. pp. 33-37.
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AU - Fasoli, Alberto

AU - Tenerelli, Pasquale

AU - Rolandi, Ermanno

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