Serum leptin, resistin, visfatin and adiponectin levels in tumour necrosis factor receptor-associated periodic syndrome (TRAPS)

Luca Cantarini, Laura Obici, Gabriele Simonini, Rolando Cimaz, Maria Romana Bacarelli, Giampaolo Merlini, Antonio Vitale, Orso Maria Lucherini, Maria Giuseppina Brizi, Mauro Galeazzi, Antonella Fioravanti

Research output: Contribution to journalArticle

Abstract

Objectives: The aims of our study were to evaluate serum leptin, resistin, visfatin and adiponectin levels in patients with tumour necrosis factor receptorassociated periodic syndrome (TRAPS), in comparison to healthy controls, and to correlate their levels to parameters of disease activity and/or severity. Methods: Serum leptin, resistin, visfatin and adiponectin levels were obtained from 14 TRAPS patients carrying mutations involving cysteine residues, from 16 TRAPS patients carrying other mutations, and from 16 healthy controls. Demographic, clinical and laboratory parameters, including amyloidosis were entered for each patient. Comparisons between groups as well as reciprocal comparisons have been evaluated. Results: Serum leptin, resistin, visfatin and adiponectin did not significantly differ among the 3 groups. Patients carrying cysteine residues mutations showed lower visfatin serum levels than patients carrying other mutations (p

Original languageEnglish
JournalClinical and Experimental Rheumatology
Volume30
Issue numberSUPPL.72
Publication statusPublished - 2012

Keywords

  • Adipokines
  • Adiponectin
  • Amyloidosis
  • Autoinflammatory disorders
  • Leptin
  • Tumour necrosis factor receptor-associated periodic syndrome (TRAPS)

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Immunology and Allergy

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    Cantarini, L., Obici, L., Simonini, G., Cimaz, R., Bacarelli, M. R., Merlini, G., Vitale, A., Lucherini, O. M., Brizi, M. G., Galeazzi, M., & Fioravanti, A. (2012). Serum leptin, resistin, visfatin and adiponectin levels in tumour necrosis factor receptor-associated periodic syndrome (TRAPS). Clinical and Experimental Rheumatology, 30(SUPPL.72).