Siero o plasma? Un quesito non nuovo che attende risposte nuove

Translated title of the contribution: Serum or plasma? An old question awaiting for new answers

Mario Plebani, Giuseppe Banfi, Sergio Bernardini, Francesco Bondanini, Laura Conti, Romolo Dorizzi, Fulvio Enrico Ferrara, Rita Mancini, Tommaso Trenti

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

There is a continual debate on what type of sample a clinical laboratory should use. While serum is still considered the gold standard and remains the required sample matrix for some assays, laboratories must consider turn-around time, which is an important metric for laboratory performance and, more importantly, plays a critical role in patient care. In addition, a body of evidence emphasize the choice of plasma samples in order to prevent modifications of some measurands due to the coagulation process and related interferences. Advantages and disadvantages of serum and plasma are discussed on the basis of current literature and evidence. In addition, data are provided on the current utilization of the matrix (serum or plasma) in Italy and in other Countries. Finally, a rational for a possible shift from serum to plasma is provided.

Original languageItalian
Pages (from-to)178-186
Number of pages9
JournalBiochimica Clinica
Volume43
Issue number2
DOIs
Publication statusPublished - Jan 1 2019

Fingerprint

Plasmas
Serum
Clinical laboratories
Turnaround time
Coagulation
Italy
Assays
Patient Care

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Medical Laboratory Technology
  • Biochemistry, medical

Cite this

Plebani, M., Banfi, G., Bernardini, S., Bondanini, F., Conti, L., Dorizzi, R., ... Trenti, T. (2019). Siero o plasma? Un quesito non nuovo che attende risposte nuove. Biochimica Clinica, 43(2), 178-186. https://doi.org/10.19186/BC_2018.069

Siero o plasma? Un quesito non nuovo che attende risposte nuove. / Plebani, Mario; Banfi, Giuseppe; Bernardini, Sergio; Bondanini, Francesco; Conti, Laura; Dorizzi, Romolo; Ferrara, Fulvio Enrico; Mancini, Rita; Trenti, Tommaso.

In: Biochimica Clinica, Vol. 43, No. 2, 01.01.2019, p. 178-186.

Research output: Contribution to journalReview article

Plebani, M, Banfi, G, Bernardini, S, Bondanini, F, Conti, L, Dorizzi, R, Ferrara, FE, Mancini, R & Trenti, T 2019, 'Siero o plasma? Un quesito non nuovo che attende risposte nuove', Biochimica Clinica, vol. 43, no. 2, pp. 178-186. https://doi.org/10.19186/BC_2018.069
Plebani M, Banfi G, Bernardini S, Bondanini F, Conti L, Dorizzi R et al. Siero o plasma? Un quesito non nuovo che attende risposte nuove. Biochimica Clinica. 2019 Jan 1;43(2):178-186. https://doi.org/10.19186/BC_2018.069
Plebani, Mario ; Banfi, Giuseppe ; Bernardini, Sergio ; Bondanini, Francesco ; Conti, Laura ; Dorizzi, Romolo ; Ferrara, Fulvio Enrico ; Mancini, Rita ; Trenti, Tommaso. / Siero o plasma? Un quesito non nuovo che attende risposte nuove. In: Biochimica Clinica. 2019 ; Vol. 43, No. 2. pp. 178-186.
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