Serum osteocalcin in metabolic bone diseases: What is its real significance?

S. Minisola, V. Carnevale, M. T. Pacitti, E. Romagnoli, L. Scarnecchia, R. Rosso, G. Minisola, G. F. Mazzuoli

Research output: Contribution to journalArticlepeer-review


This study has been carried out in order to elucidate the clinical significance of serum osteocalcin measurement. The changes of this marker paralleled those of serum total alkaline phosphatase activity (a marker of bone formation) following parathyroidectomy in hyperparathyroid patients with skeletal involvement. Furthermore, the percentage decrease of serum osteocalcin levels in respect to basal values (85±12), and the percentage decrease of serum alkaline phosphatase activity levels (82±7) were significantly lower (p

Original languageEnglish
Pages (from-to)277-279
Number of pages3
JournalJournal of Endocrinological Investigation
Issue number4
Publication statusPublished - 1993


  • calcitonin
  • Osteocalcin
  • primary hyperparathyroidism

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism


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