Serum selenium and coronary heart disease risk factors in southern Italian men

Fabrizio Jossa, Maurizio Trevisan, Vittorio Krogh, Eduardo Farinaro, Dante Giumetti, Giuseppe Fusco, Rocco Galasso, Salvatore Paneco, Sonia Frascatore, Cristina Mellone, Mario Mancini

Research output: Contribution to journalArticlepeer-review

Abstract

The association between serum selenium concentration and a number of coronary heart disease risk factors is studied in 364 males from southern Italy participating in the Olivetti Heart Study. Selenium correlates positively and significantly with serum cholesterol (r = 0.120; P = 0.022), and this positive association persists after adjustment for age and body mass index. Selenium levels in heavy smokers are lower than both light smokers and current non-smokers, but these differences do not reach statistical significance. Selenium is not significantly associated with any of the other CHD risk factors (e.g., triglycerides, HDL cholesterol, blood pressure, age, and body mass index). It is hypothesized that the association between selenium and serum cholesterol reported in this and previous studies could be due to dietary interrelationships between selenium intake and foods that affect serum cholesterol concentrations.

Original languageEnglish
Pages (from-to)129-134
Number of pages6
JournalAtherosclerosis
Volume87
Issue number2-3
DOIs
Publication statusPublished - 1991

Keywords

  • Blood pressure
  • Coronary heart disease
  • Lipids
  • Selenium
  • Smoking
  • Trace elements

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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