Serum type I and type III procollagen peptide levels in sarcoidosis

L. Bacchella, C. Tinelli, L. S. Gilè, V. Peona, C. Aprile, [No Value] MGorrini, L. Pasturenzi, G. Cetta, M. Luisetti

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Type I and type III are the most abundant collagens in the lung. The aim of our study was to compare type I and III procollagen peptides in sera of sarcoid patients. Sixty eight patients with sarcoidosis were studied (19 with newly recognized disease, 7 with relapsing disease, 15 with chronic disease, and 27 in stable remission). Thirty healthy volunteers served as controls. The levels of procollagen I and III peptides were determined by radioimmunoassay. Angiotensin-converting enzyme (ACE) level was evaluated by means of a colorimetric assay. In patients with newly recognized sarcoidosis, both serum procollagen I and III peptide levels were increased with respect to controls (p=0.0014 and p

Original languageEnglish
Pages (from-to)1648-1651
Number of pages4
JournalEuropean Respiratory Journal
Volume9
Issue number8
Publication statusPublished - 1996

Fingerprint

Collagen Type III
Sarcoidosis
Procollagen
Peptides
Serum
Peptidyl-Dipeptidase A
Radioimmunoassay
Healthy Volunteers
Chronic Disease
Collagen
Lung

Keywords

  • Angiotensin-converting enzyme
  • Collagens
  • Granulomata
  • Lung
  • Sarcoidosis activity

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Bacchella, L., Tinelli, C., Gilè, L. S., Peona, V., Aprile, C., MGorrini, N. V., ... Luisetti, M. (1996). Serum type I and type III procollagen peptide levels in sarcoidosis. European Respiratory Journal, 9(8), 1648-1651.

Serum type I and type III procollagen peptide levels in sarcoidosis. / Bacchella, L.; Tinelli, C.; Gilè, L. S.; Peona, V.; Aprile, C.; MGorrini, [No Value]; Pasturenzi, L.; Cetta, G.; Luisetti, M.

In: European Respiratory Journal, Vol. 9, No. 8, 1996, p. 1648-1651.

Research output: Contribution to journalArticle

Bacchella, L, Tinelli, C, Gilè, LS, Peona, V, Aprile, C, MGorrini, NV, Pasturenzi, L, Cetta, G & Luisetti, M 1996, 'Serum type I and type III procollagen peptide levels in sarcoidosis', European Respiratory Journal, vol. 9, no. 8, pp. 1648-1651.
Bacchella L, Tinelli C, Gilè LS, Peona V, Aprile C, MGorrini NV et al. Serum type I and type III procollagen peptide levels in sarcoidosis. European Respiratory Journal. 1996;9(8):1648-1651.
Bacchella, L. ; Tinelli, C. ; Gilè, L. S. ; Peona, V. ; Aprile, C. ; MGorrini, [No Value] ; Pasturenzi, L. ; Cetta, G. ; Luisetti, M. / Serum type I and type III procollagen peptide levels in sarcoidosis. In: European Respiratory Journal. 1996 ; Vol. 9, No. 8. pp. 1648-1651.
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