Abstract
Type I and type III are the most abundant collagens in the lung. The aim of our study was to compare type I and III procollagen peptides in sera of sarcoid patients. Sixty eight patients with sarcoidosis were studied (19 with newly recognized disease, 7 with relapsing disease, 15 with chronic disease, and 27 in stable remission). Thirty healthy volunteers served as controls. The levels of procollagen I and III peptides were determined by radioimmunoassay. Angiotensin-converting enzyme (ACE) level was evaluated by means of a colorimetric assay. In patients with newly recognized sarcoidosis, both serum procollagen I and III peptide levels were increased with respect to controls (p=0.0014 and p
| Original language | English |
|---|---|
| Pages (from-to) | 1648-1651 |
| Number of pages | 4 |
| Journal | European Respiratory Journal |
| Volume | 9 |
| Issue number | 8 |
| Publication status | Published - 1996 |
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Keywords
- Angiotensin-converting enzyme
- Collagens
- Granulomata
- Lung
- Sarcoidosis activity
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
Cite this
Bacchella, L., Tinelli, C., Gilè, L. S., Peona, V., Aprile, C., MGorrini, N. V., Pasturenzi, L., Cetta, G., & Luisetti, M. (1996). Serum type I and type III procollagen peptide levels in sarcoidosis. European Respiratory Journal, 9(8), 1648-1651.