TY - JOUR
T1 - Serum type I and type III procollagen peptide levels in sarcoidosis
AU - Bacchella, L.
AU - Tinelli, C.
AU - Gilè, L. S.
AU - Peona, V.
AU - Aprile, C.
AU - MGorrini, [No Value]
AU - Pasturenzi, L.
AU - Cetta, G.
AU - Luisetti, M.
PY - 1996
Y1 - 1996
N2 - Type I and type III are the most abundant collagens in the lung. The aim of our study was to compare type I and III procollagen peptides in sera of sarcoid patients. Sixty eight patients with sarcoidosis were studied (19 with newly recognized disease, 7 with relapsing disease, 15 with chronic disease, and 27 in stable remission). Thirty healthy volunteers served as controls. The levels of procollagen I and III peptides were determined by radioimmunoassay. Angiotensin-converting enzyme (ACE) level was evaluated by means of a colorimetric assay. In patients with newly recognized sarcoidosis, both serum procollagen I and III peptide levels were increased with respect to controls (p=0.0014 and p
AB - Type I and type III are the most abundant collagens in the lung. The aim of our study was to compare type I and III procollagen peptides in sera of sarcoid patients. Sixty eight patients with sarcoidosis were studied (19 with newly recognized disease, 7 with relapsing disease, 15 with chronic disease, and 27 in stable remission). Thirty healthy volunteers served as controls. The levels of procollagen I and III peptides were determined by radioimmunoassay. Angiotensin-converting enzyme (ACE) level was evaluated by means of a colorimetric assay. In patients with newly recognized sarcoidosis, both serum procollagen I and III peptide levels were increased with respect to controls (p=0.0014 and p
KW - Angiotensin-converting enzyme
KW - Collagens
KW - Granulomata
KW - Lung
KW - Sarcoidosis activity
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M3 - Article
C2 - 8866588
AN - SCOPUS:0029741270
VL - 9
SP - 1648
EP - 1651
JO - European Journal of Respiratory Diseases
JF - European Journal of Respiratory Diseases
SN - 0903-1936
IS - 8
ER -