Setting a highway for converting skin into neurons

Vania Broccoli, Massimiliano Caiazzo, Maria Teresa Dell'Anno

Research output: Contribution to journalArticlepeer-review

Abstract

Direct conversion of human skin fibroblasts into induced neuronal (iN) cells has been recently achieved by using different combinations of transcription factors eventually associated with microRNAs. These findings lay the ground for a straightforward and efficient generation of human neurons in vitro with elaborated functional properties instrumental for disease modeling and cell-based approaches of brain repair.

Original languageEnglish
Pages (from-to)322-323
Number of pages2
JournalJournal of Molecular Cell Biology
Volume3
Issue number6
DOIs
Publication statusPublished - Dec 2011

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology
  • Genetics

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