Severe chronic sensory-motor polyneuropathy: Coexistence of 3 unrelated etiologies in a type 1 diabetic patient. A case report and review of the literature

Andrea Micco, Eduardo Nobile-Orazio, Pierluigi Baron, Giancarlo Conti, Laura Napoli, Massimo Serafini, Guglielmo Scarlato, Elio Scarpini

Research output: Contribution to journalArticlepeer-review

Abstract

We present the case of a 58-year-old man, who has suffered from type 1 diabetes mellitus since he was young. He had monoclonal IgM kappa gammopathy of undetermined significance and high anti-MAG antibody titer. He developed a polyneuropathic picture with the clinical and laboratory features of chronic inflammatory demyelinating polyneuropathy within the span of approximately 2 years. He benefited from IV administration of high doses of immunoglobulins. Investigation of all parameters, but particularly of the clinical phenotype, can lead to a better definition of the polyneuropathic picture, especially for therapeutic and prognostic purposes.

Original languageEnglish
Pages (from-to)23-28
Number of pages6
JournalJournal of the Peripheral Nervous System
Volume8
Issue number1
Publication statusPublished - Mar 2003

Keywords

  • Chronic inflammatory demyelinating polyneuropathy
  • Diabetes mellitus
  • Monoclonal gammopathy of undetermined significance
  • Paraproteinemic neuropathy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

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