Severe cushing’s syndrome related to a small pulmonary carcinoid with widespread dissemination

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Abstract

Cushing’s syndrome (CS) is characterized by the overproduction of cortisol that may result in significant morbidity and mortality if left untreated. CS is very rarely caused by ectopic adrenocorticotropic hormone production from several tumors, although pulmonary neuroendocrine tumors (pNETs) are the most common etiology. It is controversial whether such tumors are more clinically aggressive than other pNETs. We herein report an unusual case of severe ectopic CS caused by a small pulmonary carcinoid in the lung with massive neoplastic dissemination to the liver. We highlight and discuss the unusual clinical onset, with diagnostic and therapeutic criticism, of this rare entity.

Original languageEnglish
Pages (from-to)477-480
Number of pages4
JournalInternal Medicine
Volume54
Issue number5
DOIs
Publication statusPublished - Mar 1 2015

Keywords

  • Bronchial carcinoids
  • Cushing’s syndrome
  • PET/CT scan

ASJC Scopus subject areas

  • Internal Medicine
  • Medicine(all)

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