We studied 13 patients with a severe early onset epilepsy. Epilepsy starts in the first year of life with febrile recurrent status epilepticus or long lasting convulsive seizures, in otherwise neurologically normal children. During the evolution: persistence of convulsive seizures often in clusters, and occurrence of minor, usually partial, seizures; later occurrence of interictal myoclonus at rest, cerebellar and/or pyramidal signs, mental retardation; EEG with slow background activity, multifocal and diffuse epileptic discharges. The severity of this electroclinical picture could be related to early recurrence and later persistence of long lasting convulsive seizures and to heavy therapy from the onset.
|Title of host publication||Bollettino - Lega Italiana contro l'Epilessia|
|Number of pages||2|
|Publication status||Published - 1988|
ASJC Scopus subject areas
- Clinical Neurology