Severe head injury in early infancy: Analysis of causes and possible predictive factors for outcome

Elisabetta Marton, Marina Mazzucco, Ennio Nascimben, Andrea Martinuzzi, Pierluigi Longatti

Research output: Contribution to journalArticlepeer-review


Object: The aim of this study was to analyse the causes and prognostic factors for outcome in severe traumatic brain injuries (TBI) in early infancy. Materials and methods: We present a retrospective study on 16 infants aged less than 12 months observed over the last 20 years in our department for severe brain injury. Infants were evaluated by the Children Coma Scale (CCS). We assessed Glasgow Outcome Scale (GOS) at discharge and at 12 months after discharge. Conclusions: The main causes of trauma were domestic accidents followed by car accidents. The highest positive correlation was found between the GOS score at 1 year and the presence of hypoxia and hypotension at admission, the presence of hyperglycaemia at 24 h and the occurrence of major clotting disorders. A significant but weaker correlation was found with the CCS at admission, the occurrence of early post-traumatic seizures and the length of stay in the intensive care unit.

Original languageEnglish
Pages (from-to)873-880
Number of pages8
JournalChild's Nervous System
Issue number8
Publication statusPublished - Aug 2007


  • Childhood trauma
  • Functional outcome
  • Paediatric coma scales
  • Paediatric head injury
  • Prognostic factors

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology


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