Severe hyperlipemia in a young child with diabetic ketoacidosis

Carla Bizzarri, S. Calandra, M. Cappa

Research output: Contribution to journalArticle

Abstract

Hypertriglyceridemia is common in poorly controlled diabetes. Triglyceride levels above 2000 mg/dl may result from an underlying genetic hyperlipemia, especially in patients with type 2 diabetes. Severe hyperlipemia with milky plasma has been described also at the onset of type 1 diabetes, but in this case it is usually transient. We report the case of a young child with massive hyperlipemia during ketoacidosis. No mutation of candidate genes was found. A transient lipoprotein lipase defect induced by insulin deficiency, in addition to insulin resistance, contributed to determine hyperlipemia.

Original languageEnglish
Pages (from-to)358-361
Number of pages4
JournalItalian Journal of Pediatrics
Volume32
Issue number6
Publication statusPublished - Dec 2006

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Keywords

  • Child
  • Diabetes
  • Insulin
  • Ketoacidosis
  • Lipids

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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