Severe Legionella pneumophila infection in a patient with hairy cell leukemia in partial remission after α interferon treatment

F. Radaelli, M. Langer, O. Chiorboli, D. Proietti, L. Baldini

Research output: Contribution to journalArticlepeer-review

Abstract

Legionella pneumonia is an increasingly frequently reported complication in immunocompromised patients, particularly patients with hairy cell leukemia (HCL) in active phase. The most important predisposing factor seems to be the quantitative and qualitative defect of the monocytic-macrophagic system characteristic of HCL. We report a case of severe Legionella pneumophila infection with multisystem involvement in a patient with HCL in stable partial remission obtained after therapy with interferon. In our patient recovery of a normal monocyte count did not protect against a legionella infection, indicating that this pathogen should always be sought in HCL patients even those in clinical and hematologic remission. Early diagnosis and appropriate treatment may reduce the mortality of this serious complication.

Original languageEnglish
Pages (from-to)125-128
Number of pages4
JournalHematological Oncology
Volume9
Issue number3
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Cancer Research
  • Hematology
  • Oncology

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