Severe periodontitis in young adults is associated with sub-clinical atherosclerosis

Francesco Cairo, Sergio Castellani, Anna Maria Gori, Michele Nieri, Giorgia Baldelli, Rosanna Abbate, Giovan Paolo Pini-Prato

Research output: Contribution to journalArticlepeer-review


Aim: The aim of this study was to evaluate the association between severe periodontitis and sub-clinical atherosclerosis in young (≤40 years) systemically healthy individuals. Material and Methods: Ninety systemically healthy subjects, 45 affected by severe periodontitis (mean age 36.35±3.65 years) and 45 controls without a history of periodontal disease (mean age 33.78±3.28 years), were enrolled in this study. Patients and controls were paired for age, gender, body mass index and smoking habits. Carotid intima-media thickness (IMT) was bilaterally assessed by ultrasonography at the level of common carotid artery. Traditional cardiovascular risk factors for atherosclerosis were also evaluated. Results: The overall mean carotid IMT was 0.82±0.13 mm in the test group and 0.72±0.07 mm in the control group (p

Original languageEnglish
Pages (from-to)465-472
Number of pages8
JournalJournal of Clinical Periodontology
Issue number6
Publication statusPublished - Jun 2008


  • Cardiovascular disease
  • Carotid intima-media thickness
  • Periodontal disease
  • Periodontal medicine
  • Sub-clinical atherosclerosis

ASJC Scopus subject areas

  • Dentistry(all)


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