Severe polyuria and polydipsia in hyponatremic-hypertensive syndrome associated with Wilms tumor

Paolo D'Angelo, Serena Catania, Giusy Zirilli, Paola Collini, Serena Tropia, Daniela Perotti, Monica Terenziani, Filippo Spreafico

Research output: Contribution to journalArticlepeer-review

Abstract

The combination of hyponatremia and renovascular hypertension is known as hyponatremic-hypertensive syndrome (HHS) and so rarely described in children but associated with various kinds of occlusions of the renal artery. We describe two children who presented HHS with severe hypokalemia, polyuria, and polydipsia associated with Wilms tumor, which required treatment with an angiotensin-converting enzyme inhibitor before nephrectomy. All HHS signs and symptoms resolved only following surgical resection of the tumor, allowingc hemotherapy to be given.

Original languageEnglish
Pages (from-to)566-569
Number of pages4
JournalPediatric Blood and Cancer
Volume55
Issue number3
DOIs
Publication statusPublished - Sep 2010

Keywords

  • Hypertension
  • Hypokalemia
  • Hyponatremia
  • Polydipsia
  • Polyuria
  • Wilms tumor

ASJC Scopus subject areas

  • Oncology
  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Medicine(all)

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