TY - JOUR
T1 - Severe ventricular dysrhythmias and silent ischemia during infusion of the antimetabolite 5-fluorouracil and cis-platin
AU - Hrovatin, Enzo
AU - Viel, Elda
AU - Lestuzzi, Chiara
AU - Tartuferi, Lucia
AU - Zardo, Fabio
AU - Brieda, Marco
AU - Dametto, Ermanno
AU - Piazza, Rita
AU - Antonini-Canterin, Francesco
AU - Vaccher, Elda
AU - Meneguzzo, Nereo
AU - Nicolosi, Gian Luigi
PY - 2006/8
Y1 - 2006/8
N2 - The antimetabolite 5-fluorouracil is frequently used in the therapy of various malignancies. Cardiotoxicity has frequently been described during treatment, but there is no common agreement on the need to perform cardiovascular monitoring of patients during 5-fluorouracil administration. We report the case of a young patient with an head-neck cancer on whom a continuous electrocardiogram recording was performed, documenting serious ventricular dysrhythmias in the presence of myocardial ischemia during 5-fluorouracil and cis-platin infusion.
AB - The antimetabolite 5-fluorouracil is frequently used in the therapy of various malignancies. Cardiotoxicity has frequently been described during treatment, but there is no common agreement on the need to perform cardiovascular monitoring of patients during 5-fluorouracil administration. We report the case of a young patient with an head-neck cancer on whom a continuous electrocardiogram recording was performed, documenting serious ventricular dysrhythmias in the presence of myocardial ischemia during 5-fluorouracil and cis-platin infusion.
KW - 5-fluorouracil
KW - Cardiotoxicity
KW - Chemotherapy
KW - cis-platin
KW - Malignant dysrhythmias
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UR - http://www.scopus.com/inward/citedby.url?scp=33748458673&partnerID=8YFLogxK
U2 - 10.2459/01.JCM.0000237914.12915.dd
DO - 10.2459/01.JCM.0000237914.12915.dd
M3 - Article
C2 - 16858245
AN - SCOPUS:33748458673
VL - 7
SP - 637
EP - 640
JO - Journal of Cardiovascular Medicine
JF - Journal of Cardiovascular Medicine
SN - 1558-2027
IS - 8
ER -