Severe ventricular dysrhythmias and silent ischemia during infusion of the antimetabolite 5-fluorouracil and cis-platin

Enzo Hrovatin; Elda Viel; Chiara Lestuzzi; Lucia Tartuferi; Fabio Zardo; Marco Brieda; Ermanno Dametto; Rita Piazza; Francesco Antonini-Canterin; Elda Vaccher; Nereo Meneguzzo; Gian Luigi Nicolosi

doi:10.2459/01.JCM.0000237914.12915.dd

Severe ventricular dysrhythmias and silent ischemia during infusion of the antimetabolite 5-fluorouracil and cis-platin

Enzo Hrovatin, Elda Viel, Chiara Lestuzzi, Lucia Tartuferi, Fabio Zardo, Marco Brieda, Ermanno Dametto, Rita Piazza, Francesco Antonini-Canterin, Elda Vaccher, Nereo Meneguzzo, Gian Luigi Nicolosi

Centro di Riferimento Oncologico

Research output: Contribution to journal › Article

Abstract

The antimetabolite 5-fluorouracil is frequently used in the therapy of various malignancies. Cardiotoxicity has frequently been described during treatment, but there is no common agreement on the need to perform cardiovascular monitoring of patients during 5-fluorouracil administration. We report the case of a young patient with an head-neck cancer on whom a continuous electrocardiogram recording was performed, documenting serious ventricular dysrhythmias in the presence of myocardial ischemia during 5-fluorouracil and cis-platin infusion.

Original language	English
Pages (from-to)	637-640
Number of pages	4
Journal	Journal of Cardiovascular Medicine
Volume	7
Issue number	8
DOIs	https://doi.org/10.2459/01.JCM.0000237914.12915.dd
Publication status	Published - Aug 2006

Keywords

5-fluorouracil
Cardiotoxicity
Chemotherapy
cis-platin
Malignant dysrhythmias

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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Hrovatin, E., Viel, E., Lestuzzi, C., Tartuferi, L., Zardo, F., Brieda, M., Dametto, E., Piazza, R., Antonini-Canterin, F., Vaccher, E., Meneguzzo, N., & Nicolosi, G. L. (2006). Severe ventricular dysrhythmias and silent ischemia during infusion of the antimetabolite 5-fluorouracil and cis-platin. Journal of Cardiovascular Medicine, 7(8), 637-640. https://doi.org/10.2459/01.JCM.0000237914.12915.dd

Severe ventricular dysrhythmias and silent ischemia during infusion of the antimetabolite 5-fluorouracil and cis-platin. / Hrovatin, Enzo; Viel, Elda; Lestuzzi, Chiara; Tartuferi, Lucia; Zardo, Fabio; Brieda, Marco; Dametto, Ermanno; Piazza, Rita; Antonini-Canterin, Francesco; Vaccher, Elda; Meneguzzo, Nereo; Nicolosi, Gian Luigi.

In: Journal of Cardiovascular Medicine, Vol. 7, No. 8, 08.2006, p. 637-640.

Research output: Contribution to journal › Article

Hrovatin, E, Viel, E, Lestuzzi, C, Tartuferi, L, Zardo, F, Brieda, M, Dametto, E, Piazza, R, Antonini-Canterin, F, Vaccher, E, Meneguzzo, N & Nicolosi, GL 2006, 'Severe ventricular dysrhythmias and silent ischemia during infusion of the antimetabolite 5-fluorouracil and cis-platin', Journal of Cardiovascular Medicine, vol. 7, no. 8, pp. 637-640. https://doi.org/10.2459/01.JCM.0000237914.12915.dd

Hrovatin, Enzo ; Viel, Elda ; Lestuzzi, Chiara ; Tartuferi, Lucia ; Zardo, Fabio ; Brieda, Marco ; Dametto, Ermanno ; Piazza, Rita ; Antonini-Canterin, Francesco ; Vaccher, Elda ; Meneguzzo, Nereo ; Nicolosi, Gian Luigi. / Severe ventricular dysrhythmias and silent ischemia during infusion of the antimetabolite 5-fluorouracil and cis-platin. In: Journal of Cardiovascular Medicine. 2006 ; Vol. 7, No. 8. pp. 637-640.

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