Severity grading of childhood poisoning: The multicentre study of poisoning in children (MSPC) score

Alberto G. Marchi, Nicola Bet, Maria G. Peisino, Marisa Vietti-Ramus, Maurizio Raspino, Pasquale Di Pietro, Gabriella Bernini, Lina Cantini, Lino Chiandetti, Liviana Da Dalt, Giovanni Crichiutti, Agostino Nocerino

Research output: Contribution to journalArticle

Abstract

Scores for severity grading of childhood poisoning may be useful in comparing different causes of poisoning, in order to identify the main risks and their changes over time. The Multicentre Study of Poisoning in Children score is based on four levels of severity (1 - mild, 2 - moderate, 3 - severe, 4 - very severe) involving nine target groups: seven relating to organ systems (gastrointestinal, nervous, respiratory, circulatory, renal, hepatic, skin), one to metabolic abnormalities and one to injuries from corrosive substances. Each patient is classified by the highest level attributed to any one of the nine groups. The score has been prospectively tested in 644 symptomatic children, aged 0-13 years, admitted to six pediatric hospitals of Northern Italy from January 1, 1991 to December 31, 1993. Poisoning was categorized as mild (1) in 357 children (53.8% moderate (2) in 285 (42.9% severe (3) in 18 (2.7% and very severe (4) in 4 (0.6% No deaths occurred, Severity grading according to The Multicentre Study of Poisoning in Children score confirms the prevalence of mild and moderate poisonings in children; the score seems to be an objective method suitable for epidemiological studies in direrent countries. Its clinical usefulness deserves more investigation.

Original languageEnglish
Pages (from-to)223-231
Number of pages9
JournalClinical Toxicology
Volume33
Issue number3
DOIs
Publication statusPublished - 1995

Keywords

  • Child
  • Multicentre study
  • Poisoning
  • Severity grading

ASJC Scopus subject areas

  • Toxicology
  • Health, Toxicology and Mutagenesis

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    Marchi, A. G., Bet, N., Peisino, M. G., Vietti-Ramus, M., Raspino, M., Di Pietro, P., Bernini, G., Cantini, L., Chiandetti, L., Da Dalt, L., Crichiutti, G., & Nocerino, A. (1995). Severity grading of childhood poisoning: The multicentre study of poisoning in children (MSPC) score. Clinical Toxicology, 33(3), 223-231. https://doi.org/10.3109/15563659509017988