Severity of liver injury and atherogenic lipid profile in children with nonalcoholic fatty liver disease

Valerio Nobili, Naim Alkhouri, Andrea Bartuli, Melania Manco, Rocio Lopez, Anna Alisi, Ariel E. Feldstein

Research output: Contribution to journalArticle

Abstract

Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome. The aim of this study was to assess the relationship between severity of liver injury and atherogenic lipid profile in a large group of children with NAFLD. A total of 118 consecutive children with biopsy-proven NAFLD were included. Patients underwent extensive metabolic profiling. The NAFLD activity and fibrosis scores showed a significant positive correlation with triglyceride/HDL, total cholesterol/HDL, and LDL/HDL ratios (p

Original languageEnglish
Pages (from-to)665-670
Number of pages6
JournalPediatric Research
Volume67
Issue number6
DOIs
Publication statusPublished - Jun 2010

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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