Sex differences in coronary artery disease: Pathological observations

Kazuyuki Yahagi, Harry R. Davis, Eloisa Arbustini, Renu Virmani

Research output: Contribution to journalArticlepeer-review


Cardiovascular disease (CVD) remains the most frequent cause of death in both men and women. Many studies on CVD have included mostly men, and the knowledge about coronary artery disease (CAD) in women has largely been extrapolated from studies primarily focused on men. The influence of various risk factors is different between men and women; untoward effects of smoking of CAD are greater in women than men. Furthermore, the effect of the menopause is important in women, with higher incidence of plaque erosion in young women versus greater incidence of plaque rupture in older women. This review focuses on differences in plaque morphology in men and women presenting with sudden coronary death and acute myocardial infarction.

Original languageEnglish
Pages (from-to)260-267
Number of pages8
Issue number1
Publication statusPublished - Mar 1 2015


  • Atherosclerosis
  • Coronary artery disease
  • Menopause
  • Plaque erosion
  • Sex differences
  • Smoking

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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