Sexual dimorphism in arterial hypertension: An age-related phenomenon

Roberto Antonicelli, Rosaria Gesuita, Enrico Paciaroni

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Epidemiological, clinical and experimental evidence is available indicating that male subjects develop hypertension with a higher probability than age-matched females. The sexual dimorphism of blood pressure (BP) has been observed both in normotensive and hypertensive subjects. In order to analyze the presence of sexual dimorphism of arterial hypertension (AH) and its relationship to the aging process - particularly to the menopause - the population screened in the Camerano Study has been examined. In addition, to evaluate sex-related differences in the AH, another sample of 3765 patients from our Hypertension Centre has also been considered. Our samples displayed a real cross-over in the prevalence of arterial hypertension, hypercolesterolemia, hyperglycemia and obesity in women versus men, after the menopausal period. In fact, in the adult group (20-54 years) the prevalence of arterial hypertension was significantly higher (P <0.005) in males (9.2%) than females (6.4%), whereas in the older group (>54 years), we observed a significantly higher prevalence (P <0.001) in females (46.6%) than in males (34.7%). These results suggest that the menopause and age can play a separate role in the sexual dimorphism of arterial hypertension. A significant gender- related difference in hypertensive patients was found only in hypercholesterolemia above the age of 50 years, namely, females have this disorder more frequently.

Original languageEnglish
Pages (from-to)283-289
Number of pages7
JournalArchives of Gerontology and Geriatrics
Volume29
Issue number3
DOIs
Publication statusPublished - Feb 2000

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hypertension
Sex Characteristics
Hypertension
menopause
Menopause
Hypercholesterolemia
Hyperglycemia
Obesity
Blood Pressure
gender
Population
evidence
Group

Keywords

  • Arterial hypertension
  • Human aging
  • Menopause
  • Sexual dimorphism

ASJC Scopus subject areas

  • Ageing
  • Medicine(all)

Cite this

Sexual dimorphism in arterial hypertension : An age-related phenomenon. / Antonicelli, Roberto; Gesuita, Rosaria; Paciaroni, Enrico.

In: Archives of Gerontology and Geriatrics, Vol. 29, No. 3, 02.2000, p. 283-289.

Research output: Contribution to journalArticle

Antonicelli, Roberto ; Gesuita, Rosaria ; Paciaroni, Enrico. / Sexual dimorphism in arterial hypertension : An age-related phenomenon. In: Archives of Gerontology and Geriatrics. 2000 ; Vol. 29, No. 3. pp. 283-289.
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