Sexual function in adult life following passerini-glazel feminizing genitoplasty in patients with congenital adrenal hyperplasia

Arianna Lesma, Aldo Bocciardi, Stefano Corti, Giuseppe Chiumello, Patrizio Rigatti, Francesco Montorsi

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: We assessed external genitalia sensitivity and sexual function in adults with congenital adrenal hyperplasia who had undergone Passerini-Glazel feminizing genitoplasty as children, and compared them to a control group of healthy counterparts. Materials and Methods: Inclusion criteria were congenital adrenal hyperplasia, Passerini-Glazel feminizing genitoplasty, adult age and penetrative vaginal intercourse. Thermal and vibratory sensitivity of the clitoris, vagina and labia minora were analyzed using the Genito Sensory Analyzer (Medoc Ltd., Minnetonka, Minnesota). Psychosexual outcome was assessed with the Beck Depression Inventory, Zung Self-Rating Anxiety Scale, Female Sexual Distress Scale and Female Sexual Function Index. Matched analyses were performed to compare outcomes in patients to controls (healthy medical students). All statistical tests were performed using SPSS®, version 18.0 Results: A total of 12 patients (10%) entered the study. Thermal and vibratory clitoral sensitivity was significantly decreased in all patients compared to healthy controls (p

Original languageEnglish
Pages (from-to)206-211
Number of pages6
JournalJournal of Urology
Volume191
Issue number1
DOIs
Publication statusPublished - Jan 2014

Keywords

  • adrenal hyperplasia
  • congenital
  • disorders of sex development
  • female
  • genitalia
  • plastic
  • surgery
  • urogenital surgical procedures

ASJC Scopus subject areas

  • Urology

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