SFEMG in ocular myasthenia gravis diagnosis

Luca Padua, Erik Stalberg, Mauro Lomonaco, Amelia Evoli, Annapaola Batocchi, Pietro Tonali

Research output: Contribution to journalArticlepeer-review

Abstract

Background and objective: In typical cases, the patient's history and clinical examination make it possible to diagnose ocular myasthenia gravis (OMG). But, in many cases a clear clinical picture is not present and OMG diagnosis is very difficult because gold diagnostic standard tests are not available. The diagnostic tests for OMG are usually unable to display a good sensitivity and specificity simultaneously. In this paper, we studied 86 cases submitted for suspected OMG. Methods: The patients were studied clinically and with various other tests used in OMG diagnosis (SFEMG, repetitive nerve stimulation, Ab anti AChR titration, tensilon test). Results and conclusion: SFEMG showed the highest sensitivity (100%) while Ab anti AChR showed the highest specificity (100%). To our knowledge this is the largest population of suspected OMG studied using most of the diagnostic parameters, reported in the literature. Copyright (C) 2000 Elsevier Science Ireland Ltd.

Original languageEnglish
Pages (from-to)1203-1207
Number of pages5
JournalClinical Neurophysiology
Volume111
Issue number7
DOIs
Publication statusPublished - Jul 1 2000

Keywords

  • Antiacetylcholine receptor antibody
  • Edrophonium
  • Neuromuscular transmission
  • Neurophysiology
  • Ocular myasthenia gravis
  • SFEMG

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Sensory Systems
  • Physiology (medical)

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