Shedding Light on Metabotropic Glutamate Receptors

Research output: Contribution to journalShort surveypeer-review


In this issue of Cell Chemical Biology, the elegant manuscript by Rovira et al. (2016) describes a negative allosteric modulator (NAM) of mGlu4 metabotropic glutamate receptors with in vivo activity. This compound is rapidly and reversibly inactivated by light and represents a powerful pharmacological tool for the study of mGlu4 receptors in their native environment.

Original languageEnglish
Pages (from-to)887-888
Number of pages2
JournalCell Chemical Biology
Issue number8
Publication statusPublished - Aug 18 2016

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Molecular Biology
  • Molecular Medicine
  • Drug Discovery
  • Pharmacology


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