TY - JOUR
T1 - Shelhigh No-React porcine pulmonic valve conduit
T2 - A new alternative to the homograft
AU - Marianeschi, Stefano M.
AU - Iacona, Gabriele M.
AU - Seddio, Francesco
AU - Abella, Raul F.
AU - Condoluci, Claudia
AU - Cipriani, Adriano
AU - Iorio, Fiore S.
AU - Gabbay, Shlomo
AU - Marcelletti, Carlo F.
PY - 2001
Y1 - 2001
N2 - Background. The Shelhigh No-React pulmonic valve conduit is a new porcine conduit that is glutaraldehydetreated and detoxified using a proprietary heparin process. In our institution it has been implanted in 25 patients. The aim of this present contribution is to evaluate the short-term follow-up after its implantation. Methods. From November 1997 to August 1999, 25 patients (mean age, 20.2 years; range, 0.6 to 28.3 years) were operated on using this conduit. Seventeen patients underwent a Ross procedure for aortic valve disease, with the conduits implanted in anatomic position; 6 patients underwent right ventricular outflow tract reconstruction; 2 patients underwent the Rastelli operation. The follow-up was complete. Preoperative and postoperative two-dimensional echocardiography data were collected. Results. There were two non-conduit-related deaths. Two conduits needed to be exchanged because of an increase in the gradient. Overall, all patients were improved in terms of New York Heart Association class. Comparison of preoperative and postoperative two-dimensional echocardiography gradient showed significant improvement. At the 30-month follow-up, no calcification was seen on the explanted conduits or on the two-dimensional echocardiography, although many of the patients are children. Conclusions. The Shelhigh conduits seem to be an alternative to homograft especially in infants. These experiences are preliminary, and longer follow-up is required.
AB - Background. The Shelhigh No-React pulmonic valve conduit is a new porcine conduit that is glutaraldehydetreated and detoxified using a proprietary heparin process. In our institution it has been implanted in 25 patients. The aim of this present contribution is to evaluate the short-term follow-up after its implantation. Methods. From November 1997 to August 1999, 25 patients (mean age, 20.2 years; range, 0.6 to 28.3 years) were operated on using this conduit. Seventeen patients underwent a Ross procedure for aortic valve disease, with the conduits implanted in anatomic position; 6 patients underwent right ventricular outflow tract reconstruction; 2 patients underwent the Rastelli operation. The follow-up was complete. Preoperative and postoperative two-dimensional echocardiography data were collected. Results. There were two non-conduit-related deaths. Two conduits needed to be exchanged because of an increase in the gradient. Overall, all patients were improved in terms of New York Heart Association class. Comparison of preoperative and postoperative two-dimensional echocardiography gradient showed significant improvement. At the 30-month follow-up, no calcification was seen on the explanted conduits or on the two-dimensional echocardiography, although many of the patients are children. Conclusions. The Shelhigh conduits seem to be an alternative to homograft especially in infants. These experiences are preliminary, and longer follow-up is required.
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U2 - 10.1016/S0003-4975(00)02456-5
DO - 10.1016/S0003-4975(00)02456-5
M3 - Article
C2 - 11235717
AN - SCOPUS:0035113611
VL - 71
SP - 619
EP - 623
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
SN - 0003-4975
IS - 2
ER -