Shelhigh No-React porcine pulmonic valve conduit: A new alternative to the homograft

Stefano M. Marianeschi, Gabriele M. Iacona, Francesco Seddio, Raul F. Abella, Claudia Condoluci, Adriano Cipriani, Fiore S. Iorio, Shlomo Gabbay, Carlo F. Marcelletti

Research output: Contribution to journalArticlepeer-review


Background. The Shelhigh No-React pulmonic valve conduit is a new porcine conduit that is glutaraldehydetreated and detoxified using a proprietary heparin process. In our institution it has been implanted in 25 patients. The aim of this present contribution is to evaluate the short-term follow-up after its implantation. Methods. From November 1997 to August 1999, 25 patients (mean age, 20.2 years; range, 0.6 to 28.3 years) were operated on using this conduit. Seventeen patients underwent a Ross procedure for aortic valve disease, with the conduits implanted in anatomic position; 6 patients underwent right ventricular outflow tract reconstruction; 2 patients underwent the Rastelli operation. The follow-up was complete. Preoperative and postoperative two-dimensional echocardiography data were collected. Results. There were two non-conduit-related deaths. Two conduits needed to be exchanged because of an increase in the gradient. Overall, all patients were improved in terms of New York Heart Association class. Comparison of preoperative and postoperative two-dimensional echocardiography gradient showed significant improvement. At the 30-month follow-up, no calcification was seen on the explanted conduits or on the two-dimensional echocardiography, although many of the patients are children. Conclusions. The Shelhigh conduits seem to be an alternative to homograft especially in infants. These experiences are preliminary, and longer follow-up is required.

Original languageEnglish
Pages (from-to)619-623
Number of pages5
JournalAnnals of Thoracic Surgery
Issue number2
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery


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