Short and long-term clinical effects of plasma-exchange in 33 cases of myasthenia gravis

P. M. Fornasari, G. Riva, G. Piccolo, V. Cosi, M. Lombardi

Research output: Contribution to journalArticle

Abstract

The authors examine the results of plasma exchange (PE) treatment in 33 patients with myasthenia gravis, who underwent a total of 49 cycles of treatment. On the basis of clinical response, evaluated in relation to a modification of the functional state and to the duration of improvement after PE, we selected a group of 20 responsive patients ('responders' = 60.6%) and 13 non-responsive patients ('non-responders' = 39.4%). Positive effects, some only short-lasting, were observed in 24 patients (72.7%) after 32 cycles of a total of 49 cycles (65.3%). Out of the 11 most critical patients 7 (63.3%) were considered responders, given the importance and duration of the improvement they presented, while 2 other patients had clear but short-lasting improvements; in these 9 patients, the positive effects amounted to 81.2%. Factors, presumably responsible for therapeutic failure in the non-responders are discussed.

Original languageEnglish
Pages (from-to)159-162
Number of pages4
JournalInternational Journal of Artificial Organs
Volume8
Issue number3
Publication statusPublished - 1985

ASJC Scopus subject areas

  • Biophysics

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    Fornasari, P. M., Riva, G., Piccolo, G., Cosi, V., & Lombardi, M. (1985). Short and long-term clinical effects of plasma-exchange in 33 cases of myasthenia gravis. International Journal of Artificial Organs, 8(3), 159-162.